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Literature summary extracted from

  • Lah, L.; Podobnik, B.; Novak, M.; Korosec, B.; Berne, S.; Vogelsang, M.; Krasevec, N.; Zupanec, N.; Stojan, J.; Bohlmann, J.; Komel, R.
    The versatility of the fungal cytochrome P450 monooxygenase system is instrumental in xenobiotic detoxification (2011), Mol. Microbiol., 81, 1374-1389.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.14.1 expressed in Escherichia coli strain C43(DE3) Curvularia lunata

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.1 RH + [reduced NADPH-hemoprotein reductase] + O2 Curvularia lunata
-
 ROH + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.1 Curvularia lunata
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.1 3-methoxybenzoic acid + [reduced NADPH-hemoprotein reductase] + O2 when reconstituted with cytochrome P450 reductase 2, CYP53A15 converts 3-methoxybenzoic acid to 3,4-dihydroxybenzoic acid Curvularia lunata 3,4-dihydroxybenzoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.1 3-methoxybenzoic acid + [reduced NADPH-hemoprotein reductase] + O2 when reconstituted with cytochrome P450 reductase 1, CYP53A15 converts 3-methoxybenzoic acid to 3-hydroxybenzoic acid Curvularia lunata 3-hydroxybenzoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.1 benzoic acid + [reduced NADPH-hemoprotein reductase] + O2 when reconstituted with cytochrome P450 reductase 1, CYP53A15 converts benzoic acid to 4-hydroxybenzoic acid Curvularia lunata 4-hydroxybenzoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.1 benzoic acid + [reduced NADPH-hemoprotein reductase] + O2 when reconstituted with cytochrome P450 reductase 2, CYP53A15 converts benzoic acid to 3,4-dihydroxybenzoic acid Curvularia lunata 3,4-dihydroxybenzoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.1 RH + [reduced NADPH-hemoprotein reductase] + O2
-
 Curvularia lunata ROH + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.1 BPH
-
 Curvularia lunata
1.14.14.1 CYP53A15
-
 Curvularia lunata
1.14.14.1 cytochrome P450 reductase
-
 Curvularia lunata

General Information

EC Number General Information Comment Organism
1.14.14.1 physiological function CPR1 is important in primary metabolism, whereas CPR2 plays a role in xenobiotic detoxification Curvularia lunata