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Literature summary extracted from

  • Stoyanov, A.; Petrova, P.; Lyutskanova, D.; Lahtchev, K.
    Structural and functional analysis of PUR2,5 gene encoding bifunctional enzyme of de novo purine biosynthesis in Ogataea (Hansenula) polymorpha CBS 4732(T.) (2014), Microbiol. Res., 169, 378-387.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.4.13 ATP + 5-phospho-D-ribosylamine + glycine Ogataea angusta
-
 ADP + phosphate + N1-(5-phospho-D-ribosyl)glycinamide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.4.13 Ogataea angusta G8EWC8 synonym Hansenula polymorpha
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.4.13 ATP + 5-phospho-D-ribosylamine + glycine
-
 Ogataea angusta ADP + phosphate + N1-(5-phospho-D-ribosyl)glycinamide
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.3.4.13 GARS
-
 Ogataea angusta
6.3.4.13 glycinamide ribotide synthetase
-
 Ogataea angusta
6.3.4.13 PUR2,5
-
 Ogataea angusta

Cofactor

EC Number Cofactor Comment Organism Structure
6.3.4.13 ATP
-
 Ogataea angusta

General Information

EC Number General Information Comment Organism
6.3.4.13 metabolism Pur2,5 encodes a bifunctional enzyme that catalyzes the second and the fifth steps of de novo purine biosynthesis pathway andshows dual enzymatic activity - of glycinamide ribotide synthetase and of aminoim-idazole ribotide synthetase Ogataea angusta