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Holocarboxylase synthetase interacts physically with euchromatic histone-lysine N-methyltransferase, linking histone biotinylation with methylation events

Li, Y.; Hassan, Y.I.; Moriyama, H.; Zempleni, J.; J. Nutr. Biochem. 24, 1446-1452 (2013)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
6.3.4.10
ATP + biotin + apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)]
Homo sapiens
-
AMP + diphosphate + [propionyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
6.3.4.10
Homo sapiens
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
6.3.4.10
ATP + biotin + apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
728180
Homo sapiens
AMP + diphosphate + [propionyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
-
-
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
6.3.4.10
ATP
-
Homo sapiens
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
6.3.4.10
ATP
-
Homo sapiens
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
6.3.4.10
ATP + biotin + apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)]
Homo sapiens
-
AMP + diphosphate + [propionyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
6.3.4.10
ATP + biotin + apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
728180
Homo sapiens
AMP + diphosphate + [propionyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
-
-
?
General Information
EC Number
General Information
Commentary
Organism
6.3.4.10
metabolism
holocarboxylase synthetase catalyzes the binding of the vitamin biotin to histones H3 and H4, thereby creating rare histone biotinylation marks in the epigenome. The enzyme interacts physically with euchromatic histone-lysine N-methyltransferase
Homo sapiens
General Information (protein specific)
EC Number
General Information
Commentary
Organism
6.3.4.10
metabolism
holocarboxylase synthetase catalyzes the binding of the vitamin biotin to histones H3 and H4, thereby creating rare histone biotinylation marks in the epigenome. The enzyme interacts physically with euchromatic histone-lysine N-methyltransferase
Homo sapiens