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Literature summary extracted from

  • Hagemeier, C.H.; Shima, S.; Thauer, R.K.; Bourenkov, G.; Bartunik, H.D.; Ermler, U.
    Coenzyme F420-dependent methylenetetrahydromethanopterin dehydrogenase (Mtd) from Methanopyrus kandleri: a methanogenic enzyme with an unusual quarternary structure (2003), J. Mol. Biol., 332, 1047-1057.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.5.98.1 the selenomethionine-labelled form of the enzyme is structurally characterized at 1.54 A resolution Methanopyrus kandleri

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.98.1 5,10-methylenetetrahydromethanopterin + oxidized coenzyme F420 Methanopyrus kandleri the enzyme catalyzes the fourth reaction step of CO2-reduction to methane in methanogenic archaea 5,10-methenyltetrahydromethanopterin + reduced coenzyme F420
-
?
1.5.98.1 5,10-methylenetetrahydromethanopterin + oxidized coenzyme F420 Methanopyrus kandleri DSM 6324 the enzyme catalyzes the fourth reaction step of CO2-reduction to methane in methanogenic archaea 5,10-methenyltetrahydromethanopterin + reduced coenzyme F420
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.5.98.1 Methanopyrus kandleri P94951
-
-
1.5.98.1 Methanopyrus kandleri DSM 6324 P94951
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.98.1 5,10-methylenetetrahydromethanopterin + oxidized coenzyme F420 the enzyme catalyzes the fourth reaction step of CO2-reduction to methane in methanogenic archaea Methanopyrus kandleri 5,10-methenyltetrahydromethanopterin + reduced coenzyme F420
-
?
1.5.98.1 5,10-methylenetetrahydromethanopterin + oxidized coenzyme F420 the enzyme catalyzes the fourth reaction step of CO2-reduction to methane in methanogenic archaea Methanopyrus kandleri DSM 6324 5,10-methenyltetrahydromethanopterin + reduced coenzyme F420
-
?

Subunits

EC Number Subunits Comment Organism
1.5.98.1 homohexamer
-
Methanopyrus kandleri

Synonyms

EC Number Synonyms Comment Organism
1.5.98.1 coenzyme F420-dependent methylenetetrahydromethanopterin dehydrogenase
-
Methanopyrus kandleri