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Literature summary extracted from

  • Sobierajska, K.; Skurzynski, S.; Stasiak, M.; Kryczka, J.; Cierniewski, C.S.; Swiatkowska, M.
    Protein disulfide isomerase directly interacts with beta-actin Cys374 and regulates cytoskeleton reorganization (2014), J. Biol. Chem., 289, 5758-5773.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.3.4.1 cytosol
-
 Mus musculus 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
5.3.4.1 65000
-
 x * 65000, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.3.4.1 Insulin-(SS) + GSH Mus musculus
-
 Insulin-(SH)2 + GSSG
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.3.4.1 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.3.4.1 MEG-01 cell
-
 Mus musculus
-
5.3.4.1 megakaryocyte cell line
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.4.1 Insulin-(SS) + GSH
-
 Mus musculus Insulin-(SH)2 + GSSG
-
 ?
5.3.4.1 RNase the enzyme is able to renature the denatured and reduced RNase Mus musculus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
5.3.4.1 ? x * 65000, SDS-PAGE Mus musculus

Synonyms

EC Number Synonyms Comment Organism
5.3.4.1 PDI
-
 Mus musculus
5.3.4.1 protein disulfide isomerase
-
 Mus musculus

General Information

EC Number General Information Comment Organism
5.3.4.1 physiological function protein disulfide isomerase directly interacts with beta-actin Cys374 during cell adhesion and spreading and regulates cytoskeleton reorganization Mus musculus