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Literature summary extracted from

  • Furutani, A.; Harada, Y.; Shozen, K.; Yokoi, K.; Saito, M.; Satomi, M.
    Purification and properties of a histidine decarboxylase from Staphylococcus epidermidis TYH1 isolated from Japanese fish-miso (2014), Fish. Sci., 80, 93-101.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.22 NaCl 2 M, 50% residual activity, 4.3 M, residual activity is 80%, 69%, and 38% of that of the enzyme in NaCl-free conditions at pH 5.0, 5.5, 6.0, respectively Staphylococcus epidermidis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.22 1.1
-
 L-histidine pH 4.8, 37°C Staphylococcus epidermidis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.22 121000
-
 gel filtration Staphylococcus epidermidis

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.22 Staphylococcus epidermidis B3Y006
-
-
4.1.1.22 Staphylococcus epidermidis TYH1 B3Y006
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.22
-
 Staphylococcus epidermidis

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.22 32.75
-
 pH 4.8, 37°C Staphylococcus epidermidis

Storage Stability

EC Number Storage Stability Organism
4.1.1.22 -30°C, stable for 7 days Staphylococcus epidermidis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.22 L-histidine
-
 Staphylococcus epidermidis histamine + CO2
-
 ?
4.1.1.22 L-histidine
-
 Staphylococcus epidermidis TYH1 histamine + CO2
-
 ?
4.1.1.22 additional information no substrates: lysine, arginine, tyrosine, tryptophan or ornithine Staphylococcus epidermidis ?
-
 ?
4.1.1.22 additional information no substrates: lysine, arginine, tyrosine, tryptophan or ornithine Staphylococcus epidermidis TYH1 ?
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.22 multimer putative alpha-chain of 27-30 kDa, beta-chain of 7-9 kDa, and a third 35-37 kDa band, SDS-PAGE Staphylococcus epidermidis

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.1.1.22 60
-
-
 Staphylococcus epidermidis

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
4.1.1.22 83
-
 83% of maximum activity Staphylococcus epidermidis

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.22 6
-
-
 Staphylococcus epidermidis

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.1.1.22 4
-
 about 50% of maximum activity Staphylococcus epidermidis
4.1.1.22 7
-
 sharp decline in activiy above Staphylococcus epidermidis