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Literature summary extracted from

  • Vandekerckhove, J.; Schering, B., Bärmann, M.; Aktories, K.
    Clostridium perfringens iota toxin ADP-ribosylates skeletal muscle actin in Arg-177 (1987), FEBS Lett., 225, 48-52.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.31 Clostridium perfringens Q46220
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.31 NAD+ + beta-actin
-
 Clostridium perfringens nicotinamide + H+ + (ADP-ribosyl)-beta-actin modification occurs at residue Arg177 ?
2.4.2.31 NAD+ + gamma-actin
-
 Clostridium perfringens nicotinamide + H+ + (ADP-ribosyl)-gamma-actin modification occurs at residue Arg177 ?
2.4.2.31 NAD+ + muscle actin substrate source rabbit skeletal muscle Clostridium perfringens nicotinamide + H+ + (ADP-ribosyl)-muscle actin modification occurs at residue Arg177 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.2.31 iota toxin
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 Clostridium perfringens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.2.31 37
-
 assay at Clostridium perfringens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.4.2.31 7.5
-
 assay at Clostridium perfringens