Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Mauss, S.; Chaponnier, C.; Just, I.; Aktories, K.; Gabbiani, G.
    ADP-ribosylation of actin isoforms by Clostridium botulinum C2 toxin and Clostridium perfringens iota toxin (1990), Eur. J. Biochem., 194, 237-241.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.31 Clostridium botulinum
-
-
-
2.4.2.31 Clostridium perfringens Q46220
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.31 additional information no substrates: alpha-skeletal muscle actin, alpha-smooth muscle actin or alpha-cardiac muscle actin. The N-terminal region of actin isoforms define the substrate specificity for ADP-ribosylation by Clostridium botulinum C2 toxin Clostridium botulinum ?
-
 ?
2.4.2.31 NAD+ + actin Clostridium botulinum C2 toxin ADP-ribosylates actin isoforms gizzard gamma-smooth muscle actin, spleen beta- and gamma-cytoplasmic actin, and gamma-smooth muscle actin isoforms of aortic smooth muscle actin Clostridium botulinum nicotinamide + H+ + (ADP-ribosyl)-actin
-
 ?
2.4.2.31 NAD+ + actin Clostridium perfringens iota toxin ADP-ribosylates all actin isoforms tested, i.e. alpha-skeletal muscle actin, alpha-cardiac muscle actin, gizzard gamma-smooth muscle actin, spleen beta- and gamma-cytoplasmic actin, and aortic smooth muscle actin containing alpha- and gamma-smooth muscle actin isoforms Clostridium perfringens nicotinamide + H+ + (ADP-ribosyl)-actin
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.2.31 C2 toxin
-
 Clostridium botulinum