EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.4.3.3 | (3S)-3,6-diaminohexanoate | Acetoanaerobium sticklandii | - |
(3S,5S)-3,5-diaminohexanoate | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.4.3.3 | Acetoanaerobium sticklandii | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
5.4.3.3 | (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate | radical catalytic mechanism | Acetoanaerobium sticklandii |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.4.3.3 | (3S)-3,6-diaminohexanoate | - |
Acetoanaerobium sticklandii | (3S,5S)-3,5-diaminohexanoate | - |
r | |
5.4.3.3 | additional information | 5-fluorolysine as substrate binding in the active site: computational simulations, the enzyme 5,6-LAM abstracts the hydrogen atom rather than the fluorine at C5 of 5-fluorolysine and subsequent rearrangement mimicking the similar mechanism as the natural substrate of the enzyme | Acetoanaerobium sticklandii | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.4.3.3 | 5,6-LAM | - |
Acetoanaerobium sticklandii |
5.4.3.3 | lysine 5,6-aminomutase | - |
Acetoanaerobium sticklandii |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
5.4.3.3 | 5'-deoxyadenosylcobalamin | dependent on | Acetoanaerobium sticklandii | |
5.4.3.3 | pyridoxal 5'-phosphate | dependent on, molecular modeling in the reaction | Acetoanaerobium sticklandii |