EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
4.1.2.13 | A129S/A165G | activity is between 5- to more than 900fold higher than that of wild-type towards N-Cbz-aminoaldehyde derivatives | Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.1.2.13 | Escherichia coli | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.2.13 | dihydroxyacetone + phenyl [(2R)-1-oxopropan-2-yl]carbamate | i.e. (S)-N-Cbz-alaninal,substrate only for mutant A129S/A165G | Escherichia coli | phenyl [(2R,3R,4S)-3,4,6-trihydroxy-5-oxohexan-2-yl]carbamate | aldol adduct is a key intermediates for the expedient synthesis of the pyrrolidine type iminocyclitol, 2,5-imino-1,2,5-trideoxy-D-mannitol | ? | |
4.1.2.13 | dihydroxyacetone + phenyl [(2S)-1-oxopropan-2-yl]carbamate | i.e. (S)-N-Cbz-alaninal, substrate only for mutant A129S/A165G | Escherichia coli | phenyl [(2S,3R,4S)-3,4,6-trihydroxy-5-oxohexan-2-yl]carbamate | aldol adduct is a key intermediates for the expedient synthesis of the pyrrolidine type iminocyclitol, 2,5-imino-1,2,5-trideoxy-D-glucitol | ? | |
4.1.2.13 | hydroxyacetone + phenoxyacetaldehyde | substrate only for mutant A129S/A165G | Escherichia coli | ? | - |
? | |
4.1.2.13 | hydroxyacetone + phenyl (2-oxoethyl)carbamate | substrate only for mutant A129S/A165G | Escherichia coli | ? | - |
? | |
4.1.2.13 | hydroxyacetone + phenyl (3-oxopropyl)carbamate | substrate only for mutant A129S/A165G | Escherichia coli | ? | - |
? | |
4.1.2.13 | hydroxyacetone + phenyl [(2R)-1-oxopropan-2-yl]carbamate | substrate only for mutant A129S/A165G | Escherichia coli | phenyl [(2R,3R,4S)-3,4-dihydroxy-5-oxohexan-2-yl]carbamate | - |
? | |
4.1.2.13 | hydroxyacetone + phenyl [(2S)-1-oxopropan-2-yl]carbamate | substrate only for mutant A129S/A165G | Escherichia coli | phenyl [(2S,3R,4S)-3,4-dihydroxy-5-oxohexan-2-yl]carbamate | - |
? |