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Literature summary extracted from

  • Lin, Z.; Sparling, R.
    Investigation of serine hydroxymethyltransferase in methanogens (1998), Can. J. Microbiol., 44, 652-656.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.1.2.1 0.065
-
 tetrahydrofolate pH and temperature not specified in the publication Methanospirillum hungatei
2.1.2.1 0.086
-
 tetrahydrofolate pH and temperature not specified in the publication Methanosarcina barkeri
2.1.2.1 0.29
-
 L-serine pH and temperature not specified in the publication Methanosarcina barkeri
2.1.2.1 0.31
-
 L-serine pH and temperature not specified in the publication Methanospirillum hungatei

Organism

EC Number Organism UniProt Comment Textmining
2.1.2.1 Methanolobus tindarius
-
-
-
2.1.2.1 Methanosarcina barkeri Q46A52
-
-
2.1.2.1 Methanosarcina barkeri DSM 804 Q46A52
-
-
2.1.2.1 Methanospirillum hungatei
-
-
-
2.1.2.1 Methanospirillum hungatei GP1
-
-
-
2.1.2.1 Methanothrix soehngenii
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.2.1 tetrahydrofolate + L-serine
-
 Methanothrix soehngenii 5,10-methylenetetrahydrofolate + glycine + H2O
-
 ?
2.1.2.1 tetrahydrofolate + L-serine
-
 Methanospirillum hungatei 5,10-methylenetetrahydrofolate + glycine + H2O
-
 ?
2.1.2.1 tetrahydrofolate + L-serine
-
 Methanolobus tindarius 5,10-methylenetetrahydrofolate + glycine + H2O
-
 ?
2.1.2.1 tetrahydrofolate + L-serine
-
 Methanosarcina barkeri 5,10-methylenetetrahydrofolate + glycine + H2O
-
 ?
2.1.2.1 tetrahydrofolate + L-serine
-
 Methanospirillum hungatei GP1 5,10-methylenetetrahydrofolate + glycine + H2O
-
 ?
2.1.2.1 tetrahydrofolate + L-serine
-
 Methanosarcina barkeri DSM 804 5,10-methylenetetrahydrofolate + glycine + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.2.1 SHMT
-
 Methanothrix soehngenii
2.1.2.1 SHMT
-
 Methanospirillum hungatei
2.1.2.1 SHMT
-
 Methanolobus tindarius
2.1.2.1 SHMT
-
 Methanosarcina barkeri

Cofactor

EC Number Cofactor Comment Organism Structure
2.1.2.1 pyridoxal 5'-phosphate stimulates activity Methanospirillum hungatei
2.1.2.1 pyridoxal 5'-phosphate stimulates activity Methanosarcina barkeri