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Literature summary extracted from

  • Vemparala, S.; Mehrotra, S.; Balaram, H.
    Role of loop dynamics in thermal stability of mesophilic and thermophilic adenylosuccinate synthetase: a molecular dynamics and normal mode analysis study (2011), Biochim. Biophys. Acta, 1814, 630-637.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.4.4 GTP + IMP + L-Asp Escherichia coli
-
 GDP + phosphate + adenylosuccinate
-
 ?
6.3.4.4 GTP + IMP + L-Asp Pyrococcus horikoshii
-
 GDP + phosphate + adenylosuccinate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.4.4 Escherichia coli P0A7D4
-
-
6.3.4.4 Pyrococcus horikoshii O58187
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.4.4 GTP + IMP + L-Asp
-
 Escherichia coli GDP + phosphate + adenylosuccinate
-
 ?
6.3.4.4 GTP + IMP + L-Asp
-
 Pyrococcus horikoshii GDP + phosphate + adenylosuccinate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.3.4.4 Adenylosuccinate synthetase
-
 Escherichia coli
6.3.4.4 Adenylosuccinate synthetase
-
 Pyrococcus horikoshii
6.3.4.4 AdSS
-
 Escherichia coli
6.3.4.4 AdSS
-
 Pyrococcus horikoshii

Cofactor

EC Number Cofactor Comment Organism Structure
6.3.4.4 GTP
-
 Escherichia coli
6.3.4.4 GTP
-
 Pyrococcus horikoshii