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Literature summary extracted from

  • Prosser, G.A.; de Carvalho, L.P.
    Reinterpreting the mechanism of inhibition of Mycobacterium tuberculosis D-alanine:D-alanine ligase by D-cycloserine (2013), Biochemistry, 52, 7145-7149.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.3.2.4 D-cycloserine a slow-onset inhibitor specifically to the Mycobacterium tuberculosis enzyme orthologue, inhibition mechanism, overview. D-Cycloserine binds exclusively to the C-terminal D-alanine binding site, even in the absence of bound D-alanine at the N-terminal binding site Mycobacterium tuberculosis

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.4 Mycobacterium tuberculosis
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-
-

Synonyms

EC Number Synonyms Comment Organism
6.3.2.4 D-Alanine:D-alanine ligase
-
 Mycobacterium tuberculosis
6.3.2.4 Ddl
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 Mycobacterium tuberculosis