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Literature summary extracted from

  • Haraikawa, M.; Tsugawa, N.; Sogabe, N.; Tanabe, R.; Kawamura, Y.; Okano, T.; Hosoi, T.; Goseki-Sone, M.
    Effects of gamma-glutamyl carboxylase gene polymorphism (R325Q) on the association between dietary vitamin K intake and gamma-carboxylation of osteocalcin in young adults (2013), Asia Pac. J. Clin. Nutr., 22, 646-654.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
4.1.1.90 R325Q the mutation is associated with the bone mineral density Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.90 peptidyl-4-carboxyglutamate + 2,3-epoxyphylloquinone + H2O Homo sapiens
-
 peptidyl-glutamate + CO2 + O2 + phylloquinone
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.90 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.90 blood
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.90 peptidyl-4-carboxyglutamate + 2,3-epoxyphylloquinone + H2O
-
 Homo sapiens peptidyl-glutamate + CO2 + O2 + phylloquinone
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.90 gamma-glutamyl carboxylase
-
 Homo sapiens
4.1.1.90 GGCX
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.90 vitamin K
-
 Homo sapiens