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Literature summary extracted from

  • Peters-Wendisch, P.; Stansen, K.C.; Goetker, S.; Wendisch, V.F.
    Biotin protein ligase from Corynebacterium glutamicum: role for growth and L: -lysine production (2012), Appl. Microbiol. Biotechnol., 93, 2493-2502.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.3.4.15 expressed in Escherichia coli DH5alpha cells Corynebacterium glutamicum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.4.14 ATP + biotin-carboxyl-carrier protein + HCO3- Corynebacterium glutamicum
-
 ADP + phosphate + carboxybiotin-carboxyl-carrier protein
-
 ?
6.3.4.14 ATP + biotin-carboxyl-carrier protein + HCO3- Corynebacterium glutamicum ATCC 13032
-
 ADP + phosphate + carboxybiotin-carboxyl-carrier protein
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.4.14 Corynebacterium glutamicum
-
-
-
6.3.4.14 Corynebacterium glutamicum ATCC 13032
-
-
-
6.3.4.15 Corynebacterium glutamicum Q8NSG6
-
-
6.3.4.15 Corynebacterium glutamicum ATCC 13032 Q8NSG6
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.4.14 ATP + biotin-carboxyl-carrier protein + HCO3-
-
 Corynebacterium glutamicum ADP + phosphate + carboxybiotin-carboxyl-carrier protein
-
 ?
6.3.4.14 ATP + biotin-carboxyl-carrier protein + HCO3-
-
 Corynebacterium glutamicum ATCC 13032 ADP + phosphate + carboxybiotin-carboxyl-carrier protein
-
 ?
6.3.4.15 ATP + biotin + apo-[biotin carboxyl carrier protein]
-
 Corynebacterium glutamicum AMP + diphosphate + biotinylated biotin carboxyl carrier protein
-
 ?
6.3.4.15 ATP + biotin + apo-[biotin carboxyl carrier protein]
-
 Corynebacterium glutamicum ATCC 13032 AMP + diphosphate + biotinylated biotin carboxyl carrier protein
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.3.4.14 AccBC biotin carboxylase/biotin carboxyl carrier protein subunit of acetyl CoA carboxylase Corynebacterium glutamicum
6.3.4.15 biotin protein ligase
-
 Corynebacterium glutamicum
6.3.4.15 BirA
-
 Corynebacterium glutamicum

Cofactor

EC Number Cofactor Comment Organism Structure
6.3.4.14 ATP
-
 Corynebacterium glutamicum
6.3.4.15 ATP
-
 Corynebacterium glutamicum