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Literature summary extracted from

  • Syed, K.; Porollo, A.; Lam, Y.W.; Grimmett, P.E.; Yadav, J.S.
    CYP63A2, a catalytically versatile fungal P450 monooxygenase capable of oxidizing higher-molecular-weight polycyclic aromatic hydrocarbons, alkylphenols, and alkanes (2013), Appl. Environ. Microbiol., 79, 2692-2702.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.14.1 expressed in Pichia pastoris Phanerodontia chrysosporium

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.1 Phanerodontia chrysosporium
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.1 benzo(a)pyrene + [reduced NADPH-hemoprotein reductase] + O2
-
 Phanerodontia chrysosporium ?
-
 ?
1.14.14.1 benzo(ghi)perylene + [reduced NADPH-hemoprotein reductase] + O2
-
 Phanerodontia chrysosporium ?
-
 ?
1.14.14.1 fluoranthene + [reduced NADPH-hemoprotein reductase] + O2
-
 Phanerodontia chrysosporium ?
-
 ?
1.14.14.1 additional information no activity with fluorene, anthracene, phenanthrene, and acenaphthene Phanerodontia chrysosporium ?
-
 ?
1.14.14.1 additional information the enzyme also acts as an alkane-hydroxylase that oxidizes n-alkanes with various chain lengths (C9to C12and C15to C19), as well as alkyl side chains (C3to C9) in alkylphenols. CYP63A2 shows preferential oxidation of long-chain alkylphenols and alkanes Phanerodontia chrysosporium ?
-
 ?
1.14.14.1 pyrene + [reduced NADPH-hemoprotein reductase] + O2
-
 Phanerodontia chrysosporium ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.1 CYP63A2
-
 Phanerodontia chrysosporium
1.14.14.1 cytochrome P450 monooxygenase
-
 Phanerodontia chrysosporium