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Literature summary extracted from

  • Kaesler, N.; Schettgen, T.; Mutucumarana, V.P.; Brandenburg, V.; Jahnen-Dechent, W.; Schurgers, L.J.; Krueger, T.
    A fluorescent method to determine vitamin K-dependent gamma-glutamyl carboxylase activity (2012), Anal. Biochem., 421, 411-416.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.90 5-mercapto-1-methylthiotetrazole
-
 Rattus norvegicus
4.1.1.90 N-ethylmaleimide
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.1.90 endoplasmic reticulum
-
 Rattus norvegicus 5783
-
4.1.1.90 microsome
-
 Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.90 peptidyl-4-carboxyglutamate + 2,3-epoxyphylloquinone + H2O Rattus norvegicus
-
 peptidyl-glutamate + CO2 + O2 + phylloquinone
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.90 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.90 kidney
-
 Rattus norvegicus
-
4.1.1.90 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.90 peptidyl-4-carboxyglutamate + 2,3-epoxyphylloquinone + H2O
-
 Rattus norvegicus peptidyl-glutamate + CO2 + O2 + phylloquinone
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.90 vitamin K-dependent gamma-glutamyl carboxylase
-
 Rattus norvegicus