Literature summary extracted from

Naidansuren, P.; Park, C.W.; Kim, S.H.; Nanjidsuren, T.; Park, J.J.; Yun, S.J.; Sim, B.W.; Hwang, S.; Kang, M.H.; Ryu, B.Y.; Hwang, S.Y.; Yoon, J.T.; Yamanouchi, K.; Min, K.S.
Molecular characterization of bovine placental and ovarian 20alpha-hydroxysteroid dehydrogenase (2011), Reproduction, 142, 723-731.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.1.1.149	recombinantly expressed in Escherichia coli cells and CHO cells	Bos taurus

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.1.1.149	37000	-	Western blot	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.149	Bos taurus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.1.1.149	ovary	immunohistochemical analysis shows that bovine 20alpha-HSD protein is intensively localized in the large luteal cells during the late estrous cycle	Bos taurus	-
1.1.1.149	placenta	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.149	20alpha-hydroxyprogesterone + NAD+	-	Bos taurus	progesterone + NADH	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.1.1.149	20alpha-HSD	-	Bos taurus
1.1.1.149	20alpha-hydroxysteroid dehydrogenase	-	Bos taurus

Expression

EC Number	Organism	Comment	Expression
1.1.1.149	Bos taurus	mRNA levels increase gradually throughout the estrous cycle, the highest being in the corpus luteum (CL) 1 stage	up

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Release 2023.1 (January 2023)