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Literature summary extracted from

  • Pintus, F.; Spano, D.; Floris, G.; Medda, R.
    Euphorbia characias latex amine oxidase and peroxidase: interacting enzymes? (2013), Protein J., 32, 435-441.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.21 nitric oxide irreversible inhibitor Euphorbia characias
1.4.3.21 tyramine irreversible inhibitor Euphorbia characias

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.4.3.21 Cu2+ the enzyme contains one non-blue copper type 2 ion as an inorganic cofactor Euphorbia characias

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.4.3.21 74000
-
 2 * 74000, calculated from amino acid sequence Euphorbia characias

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.21 Euphorbia characias Q9SW90
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.21 latex
-
 Euphorbia characias
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.21 additional information the enzyme oxidizes arginine to ammonia, urea, hydrogen peroxide and glutamate-5-semialdehyde which spontaneously cyclizes yielding DELTA1-pyrroline-5-carboxylic acid Euphorbia characias ?
-
 ?
1.4.3.21 ornithine + H2O + O2 ornithine can be transformed in glutamate-5-semialdehyde spontaneously cyclizes yielding DELTA1-pyrroline-5-carboxylic acid Euphorbia characias ?
-
 ?
1.4.3.21 putrescine + H2O + O2 putrescine can be oxidatively deaminated by the enzyme to corresponding aldehyde that spontaneously cyclizes yielding DELTA1-pyrroline Euphorbia characias ?
-
 ?
1.4.3.21 spermidine + H2O + O2 good substrate. The oxidation of spermidine yields to the liberation of ammonia, hydrogen peroxide and the corresponding aldehyde that spontaneously cyclizes yielding first 1-(3-aminopropyl)pyrroliniun and, thereafter, 1,5-diazobicyclononane Euphorbia characias ? + NH3 + H2O2
-
 ?
1.4.3.21 spermine + H2O + O2 good substrate Euphorbia characias ? + NH3 + H2O2
-
 ?
1.4.3.21 tyramine + H2O + O2 during this reaction, an irreversible inactivation of the enzyme occurs Euphorbia characias 4-hydroxyphenylacetaldehyde + NH3 + H2O2
-
 ?

Subunits

EC Number Subunits Comment Organism
1.4.3.21 homodimer 2 * 74000, calculated from amino acid sequence Euphorbia characias

Synonyms

EC Number Synonyms Comment Organism
1.4.3.21 copper/quinone containing amine oxidase
-
 Euphorbia characias
1.4.3.21 ELAO
-
 Euphorbia characias

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.3.21 2,4,5-trihydroxyphenylalanine quinone
-
 Euphorbia characias