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Literature summary extracted from

  • Missihoun, T.D.; Schmitz, J.; Klug, R.; Kirch, H.H.; Bartels, D.
    Betaine aldehyde dehydrogenase genes from Arabidopsis with different sub-cellular localization affect stress responses (2011), Planta, 233, 369-382.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.1.8 expressed in Escherichia coli BL21(DE3) cells Arabidopsis thaliana

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.1.8 1.1
-
 4-Aminobutyraldehyde in 100 mM sodium diphosphate pH 8.0, at 22°C Arabidopsis thaliana
1.2.1.8 3.7
-
 3-aminopropionaldehyde in 100 mM sodium diphosphate pH 8.0, at 22°C Arabidopsis thaliana
1.2.1.8 6.81
-
 Betaine aldehyde in 100 mM sodium diphosphate pH 8.0, at 22°C Arabidopsis thaliana

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.8 leucoplast
-
 Arabidopsis thaliana 9516
-
1.2.1.8 peroxisome
-
 Arabidopsis thaliana 5777
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.8 3-aminopropionaldehyde + NAD+ + H2O Arabidopsis thaliana
-
 3-aminopropionate + NADH + H+
-
 ?
1.2.1.8 4-aminobutyraldehyde + NAD+ + H2O Arabidopsis thaliana
-
 4-aminobutyric acid + NADH + H+
-
 ?
1.2.1.8 betaine aldehyde + NAD+ + H2O Arabidopsis thaliana
-
 betaine + NADH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.8 Arabidopsis thaliana Q9S795 ecotype Col-0
-
1.2.1.8 Arabidopsis thaliana Q9STS1 ecotype Col-0
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.1.8 His-Tag affinity chromatography Arabidopsis thaliana

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.8 3-aminopropionaldehyde + NAD+ + H2O
-
 Arabidopsis thaliana 3-aminopropionate + NADH + H+
-
 ?
1.2.1.8 4-aminobutyraldehyde + NAD+ + H2O
-
 Arabidopsis thaliana 4-aminobutyric acid + NADH + H+
-
 ?
1.2.1.8 betaine aldehyde + NAD+ + H2O
-
 Arabidopsis thaliana betaine + NADH + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.8 ALDH10A8
-
 Arabidopsis thaliana
1.2.1.8 ALDH10A9
-
 Arabidopsis thaliana
1.2.1.8 BADH
-
 Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.8 NAD+
-
 Arabidopsis thaliana

Expression

EC Number Organism Comment Expression
1.2.1.8 Arabidopsis thaliana the ALDH10A8 gene is weakly induced by abscisic acid, salt, chilling (4°C), methyl viologen and dehydration up
1.2.1.8 Arabidopsis thaliana the ALDH10A9 gene is weakly induced by abscisic acid, salt, chilling (4°C), methyl viologen and dehydration up

General Information

EC Number General Information Comment Organism
1.2.1.8 physiological function ALDH10A8 serves as detoxification enzyme controlling the level of aminoaldehydes, which are produced in cellular metabolism under stress conditions Arabidopsis thaliana
1.2.1.8 physiological function LDH10A9 serves as detoxification enzymes controlling the level of aminoaldehydes, which are produced in cellular metabolism under stress conditions Arabidopsis thaliana