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Literature summary extracted from

  • Timm, S.; Florian, A.; Jahnke, K.; Nunes-Nesi, A.; Fernie, A.R.; Bauwe, H.
    The hydroxypyruvate-reducing system in Arabidopsis: multiple enzymes for the same end (2011), Plant Physiol., 155, 694-705.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.81 expression in Escherichia coli Arabidopsis thaliana

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.81 chloroplast
-
 Arabidopsis thaliana 9507
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.81 glyoxylate + NADPH + H+ Arabidopsis thaliana
-
 glycolate + NADP+
-
 ?
1.1.1.81 hydroxypyruvate + NADPH Arabidopsis thaliana
-
 D-glycerate + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.81 Arabidopsis thaliana Q9LE33
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.81 glyoxylate + NADPH + H+
-
 Arabidopsis thaliana glycolate + NADP+
-
 ?
1.1.1.81 hydroxypyruvate + NADPH
-
 Arabidopsis thaliana D-glycerate + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.81 At1g12550
-
 Arabidopsis thaliana
1.1.1.81 HPR3
-
 Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.81 NADP+
-
 Arabidopsis thaliana
1.1.1.81 NADPH NADPH is preferred over NADH Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
1.1.1.81 physiological function deletion of isoform HPR3 results in slightly altered leaf concentrations of the photorespiratory intermediates HP, glycerate, and glycine, indicating a disrupted photorespiratory flux, but not in visible alteration of the phenotype.The combined deletion of of isoforms HPR1, HPR2, and HPR3 causes increased growth retardation, decreased photochemical efficiency, and reduced oxygen-dependent gas exchange in comparison with the hpr1hpr2 double mutant. Isoform HPR3 could provide a compensatory bypass for the reduction of hydroxypyruvate and glyoxylate within the chloroplast Arabidopsis thaliana