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Literature summary extracted from

  • Dehghan, E.; Shahriari Ahmadi, F.; Ghotbi Ravandi, E.; Reed, D.W.; Covello, P.S.; Bahrami, A.R.
    An atypical pattern of accumulation of scopolamine and other tropane alkaloids and expression of alkaloid pathway genes in Hyoscyamus senecionis (2013), Plant Physiol. Biochem., 70C, 188-194.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.206 tropinone + NADPH + H+ Hyoscyamus muticus tropinone reductase II pseudotropine + NADP+
-
 ?
1.1.1.206 tropinone + NADPH + H+ Hyoscyamus senecionis tropinone reductase II pseudotropine + NADP+
-
 ?
1.1.1.236 tropinone + NADPH + H+ Hyoscyamus muticus tropinone reductase I tropine + NADP+
-
 ?
1.1.1.236 tropinone + NADPH + H+ Hyoscyamus senecionis tropinone reductase I tropine + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.206 Hyoscyamus muticus
-
-
-
1.1.1.206 Hyoscyamus senecionis
-
-
-
1.1.1.236 Hyoscyamus muticus
-
-
-
1.1.1.236 Hyoscyamus senecionis
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.206 leaf hyoscyamine is the main tropane alkaloid of the leaf and root of Hyoscyamus muticus Hyoscyamus muticus
-
1.1.1.206 leaf scopolamine is the main tropane alkaloid compound in Hyoscyamus senecionis leaves Hyoscyamus senecionis
-
1.1.1.206 root hyoscyamine is the main tropane alkaloid of the leaf and root of Hyoscyamus muticus Hyoscyamus muticus
-
1.1.1.236 leaf hyoscyamine is the main tropane alkaloid of the leaf and root of Hyoscyamus muticus Hyoscyamus muticus
-
1.1.1.236 leaf scopolamine is the main tropane alkaloid compound in Hyoscyamus senecionis leaves Hyoscyamus senecionis
-
1.1.1.236 root hyoscyamine is the main tropane alkaloid of the leaf and root of Hyoscyamus muticus Hyoscyamus muticus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.206 tropinone + NADPH + H+ tropinone reductase II Hyoscyamus muticus pseudotropine + NADP+
-
 ?
1.1.1.206 tropinone + NADPH + H+ tropinone reductase II Hyoscyamus senecionis pseudotropine + NADP+
-
 ?
1.1.1.236 tropinone + NADPH + H+ tropinone reductase I Hyoscyamus muticus tropine + NADP+
-
 ?
1.1.1.236 tropinone + NADPH + H+ tropinone reductase I Hyoscyamus senecionis tropine + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.206 tropinone reductase II
-
 Hyoscyamus muticus
1.1.1.206 tropinone reductase II
-
 Hyoscyamus senecionis
1.1.1.236 tropinone reductase I
-
 Hyoscyamus muticus
1.1.1.236 tropinone reductase I
-
 Hyoscyamus senecionis

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.206 NADPH
-
 Hyoscyamus muticus
1.1.1.206 NADPH
-
 Hyoscyamus senecionis
1.1.1.236 NADPH
-
 Hyoscyamus muticus
1.1.1.236 NADPH
-
 Hyoscyamus senecionis

General Information

EC Number General Information Comment Organism
1.1.1.206 metabolism tropinone reductase II is part of biosynthesis of calystegines, overview. Hyoscyamine is the main tropane alkaloid of the leaf and root of Hyoscyamus muticus. Higher amounts of littorine as an intermediate compound in the pathway, and 3'-hydroxylittorine are accumulated in roots than in other organs Hyoscyamus muticus
1.1.1.206 metabolism tropinone reductase II is part of biosynthesis of calystegines, overview. Scopolamine is the main tropane alkaloid compound in Hyoscyamus senecionis leaves. Higher amounts of littorine as an intermediate compound in the pathway, and 3'-hydroxylittorine are accumulated in roots than in other organs Hyoscyamus senecionis
1.1.1.236 metabolism tropinone reductase I is involved in the scopolamine biosynthetic pathway, overview. Hyoscyamine is the main tropane alkaloid of the leaf and root of Hyoscyamus muticus. Higher amounts of littorine as an intermediate compound in the pathway, and 3'-hydroxylittorine are accumulated in roots than in other organs Hyoscyamus muticus
1.1.1.236 metabolism tropinone reductase I is involved in the scopolamine biosynthetic pathway, overview. Scopolamine is the main tropane alkaloid compound in Hyoscyamus senecionis leaves. Higher amounts of littorine as an intermediate compound in the pathway, and 3'-hydroxylittorine are accumulated in roots than in other organs Hyoscyamus senecionis