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Literature summary extracted from

  • Maeda, I.
    Genetic modification in Bacillus subtilis for production of C30 carotenoids (2012), Methods Mol. Biol., 892, 197-205.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.3.8.2 coexpression with dehydroqualene desarurase with dehydrosqualene synthase and induction of endogenous genes crtP and crtQ encoding mixed function oxidase and glycosyltransferase for production of glycosylated C30 carotenoic acid, overview Staphylococcus aureus
1.3.8.2 gene crtN, functional expression in Bacillus subtilis, coexpression with dehydroqualene synthase and induction of endogenous genes crtP and crtQ Staphylococcus aureus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.8.2 15-cis-4,4'-diapophytoene + 4 FAD Staphylococcus aureus
-
 all-trans-4,4'-diapolycopene + 4 FADH2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.8.2 Staphylococcus aureus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.8.2 15-cis-4,4'-diapophytoene + 4 FAD
-
 Staphylococcus aureus all-trans-4,4'-diapolycopene + 4 FADH2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.8.2 CrtN
-
 Staphylococcus aureus
1.3.8.2 dehydrosqualene desaturase
-
 Staphylococcus aureus

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.8.2 FAD
-
 Staphylococcus aureus

General Information

EC Number General Information Comment Organism
1.3.8.2 metabolism dehydrosqualene synthase converts farnesyl diphosphate to dehydrosqualene, dehydrosqualene desaturase then converts dehydrosqualene to the yelllow carotenoid 4,4'-diaponeurosporene Staphylococcus aureus