Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Wojciechowicz, B.; Kotwica, G.; Kolakowska, J.; Franczak, A.
    The activity and localization of 3beta-hydroxysteroid dehydrogenase/DELTA(5)-DELTA(4) isomerase and release of androstenedione and progesterone by uterine tissues during early pregnancy and the estrous cycle in pigs (2013), J. Reprod. Dev., 59, 49-58.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.145 Sus scrofa
-
-
-
5.3.3.1 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.145 myometrium HSDB1 transcript abundance in the endometrium and myometrium remain at the same level during the examined days of pregnancy. After luteolysis both endometrial and myometrial HSD3B1 expression wane Sus scrofa
-
1.1.1.145 uterine endometrium HSDB1 transcript abundance in the endometrium and myometrium remain at the same level during the examined days of pregnancy. After luteolysis both endometrial and myometrial HSD3B1 expression wane Sus scrofa
-
5.3.3.1 endometrium
-
 Sus scrofa
-
5.3.3.1 myometrium
-
 Sus scrofa
-
5.3.3.1 uterus
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.3.1 dehydroepiandrosterone
-
 Sus scrofa androstenedione
-
 ?
5.3.3.1 pregnenolone
-
 Sus scrofa progesterone
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.145 3beta-HSD
-
 Sus scrofa
1.1.1.145 HSDB1
-
 Sus scrofa
5.3.3.1 3beta-HSD
-
 Sus scrofa
5.3.3.1 3beta-hydroxysteroid dehydrogenase/DELTA5-DELTA4 isomerase
-
 Sus scrofa

Expression

EC Number Organism Comment Expression
1.1.1.145 Sus scrofa after luteolysis both endometrial and myometrial HSD3B1 expression wane down
1.1.1.145 Sus scrofa HSDB1 transcript abundance in the endometrium and myometrium remain at the same level during the examined days of pregnancy additional information
5.3.3.1 Sus scrofa during the estrous cycle, the endometrial enzyme activity is higher on days 10 to 11 and decreases on days 12 to 13 and days 15 to 16 up

General Information

EC Number General Information Comment Organism
5.3.3.1 physiological function the enzyme is responsible for progesterone and androstenedione production Sus scrofa