EC Number | Cloned (Comment) | Organism |
---|---|---|
1.2.1.48 | expressed in Escherichia coli | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.2.1.48 | microsome | - |
Mus musculus | - |
- |
1.2.1.48 | microsome | - |
Homo sapiens | - |
- |
1.2.1.48 | microsome | - |
Rattus norvegicus | - |
- |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.2.1.48 | 55000 | - |
2 * 55000, SDS-PAGE | Mus musculus |
1.2.1.48 | 55000 | - |
2 * 55000, SDS-PAGE | Homo sapiens |
1.2.1.48 | 55000 | - |
2 * 55000, SDS-PAGE | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.1.48 | cis,cis-9,12-octadecadienal + NAD+ + H2O | Mus musculus | major substrate | cis,cis-9,12-octadecadienoic acid + NADH | - |
? | |
1.2.1.48 | cis,cis-9,12-octadecadienal + NAD+ + H2O | Homo sapiens | major substrate | cis,cis-9,12-octadecadienoic acid + NADH | - |
? | |
1.2.1.48 | cis,cis-9,12-octadecadienal + NAD+ + H2O | Rattus norvegicus | major substrate | cis,cis-9,12-octadecadienoic acid + NADH | - |
? | |
1.2.1.48 | long-chain aldehyde + NAD+ + H2O | Mus musculus | - |
long-chain acid anion + NADH | - |
? | |
1.2.1.48 | long-chain aldehyde + NAD+ + H2O | Homo sapiens | - |
long-chain carboxylate + NADH | - |
? | |
1.2.1.48 | long-chain aldehyde + NAD+ + H2O | Rattus norvegicus | - |
long-chain carboxylate + NADH | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.2.1.48 | Homo sapiens | - |
- |
- |
1.2.1.48 | Mus musculus | - |
- |
- |
1.2.1.48 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.2.1.48 | Strep-tag affinity chromatography and AMP-Sepharose column chromatography | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.2.1.48 | adrenal gland | - |
Mus musculus | - |
1.2.1.48 | cerebellum | - |
Mus musculus | - |
1.2.1.48 | cerebrum | - |
Mus musculus | - |
1.2.1.48 | fibroblast | - |
Homo sapiens | - |
1.2.1.48 | heart | low activity | Mus musculus | - |
1.2.1.48 | kidney | - |
Mus musculus | - |
1.2.1.48 | large intestine | - |
Mus musculus | - |
1.2.1.48 | liver | - |
Mus musculus | - |
1.2.1.48 | liver | - |
Rattus norvegicus | - |
1.2.1.48 | lung | - |
Mus musculus | - |
1.2.1.48 | ovary | high activity | Mus musculus | - |
1.2.1.48 | skeletal muscle | low activity | Mus musculus | - |
1.2.1.48 | spleen | - |
Mus musculus | - |
1.2.1.48 | stomach | - |
Mus musculus | - |
1.2.1.48 | stomach | high activity | Mus musculus | - |
1.2.1.48 | subcutaneous adipose tissue | - |
Mus musculus | - |
1.2.1.48 | testis | high activity | Mus musculus | - |
1.2.1.48 | visceral fat | high activity | Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.1.48 | cis,cis-9,12-octadecadienal + NAD+ + H2O | major substrate | Mus musculus | cis,cis-9,12-octadecadienoic acid + NADH | - |
? | |
1.2.1.48 | cis,cis-9,12-octadecadienal + NAD+ + H2O | major substrate | Homo sapiens | cis,cis-9,12-octadecadienoic acid + NADH | - |
? | |
1.2.1.48 | cis,cis-9,12-octadecadienal + NAD+ + H2O | major substrate | Rattus norvegicus | cis,cis-9,12-octadecadienoic acid + NADH | - |
? | |
1.2.1.48 | long-chain aldehyde + NAD+ + H2O | - |
Mus musculus | long-chain acid anion + NADH | - |
? | |
1.2.1.48 | long-chain aldehyde + NAD+ + H2O | - |
Homo sapiens | long-chain carboxylate + NADH | - |
? | |
1.2.1.48 | long-chain aldehyde + NAD+ + H2O | - |
Rattus norvegicus | long-chain carboxylate + NADH | - |
? | |
1.2.1.48 | pyrenedecanal + NAD+ + H2O | - |
Mus musculus | pyrenedecanoic acid + NADH | - |
? | |
1.2.1.48 | pyrenedecanal + NAD+ + H2O | - |
Homo sapiens | pyrenedecanoic acid + NADH | - |
? | |
1.2.1.48 | pyrenedecanal + NAD+ + H2O | - |
Rattus norvegicus | pyrenedecanoic acid + NADH | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.2.1.48 | homodimer | 2 * 55000, SDS-PAGE | Mus musculus |
1.2.1.48 | homodimer | 2 * 55000, SDS-PAGE | Homo sapiens |
1.2.1.48 | homodimer | 2 * 55000, SDS-PAGE | Rattus norvegicus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.2.1.48 | ALDH3A2 | - |
Mus musculus |
1.2.1.48 | ALDH3A2 | - |
Homo sapiens |
1.2.1.48 | ALDH3A2 | - |
Rattus norvegicus |
1.2.1.48 | fatty aldehyde dehydrogenase | - |
Mus musculus |
1.2.1.48 | fatty aldehyde dehydrogenase | - |
Homo sapiens |
1.2.1.48 | fatty aldehyde dehydrogenase | - |
Rattus norvegicus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.2.1.48 | NAD+ | - |
Mus musculus | |
1.2.1.48 | NAD+ | - |
Homo sapiens | |
1.2.1.48 | NAD+ | - |
Rattus norvegicus |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.2.1.48 | malfunction | deficiency in fatty aldehyde dehydrogenase causes the Sjogren Larsson Syndrome, a rare inherited disorder characterized by ichthyosis, spasticity, and mental retardation | Homo sapiens |