BRENDA - Enzyme Database

Characterization and role of fucose mutarotase in mammalian cells

Park, D.; Ryu, K.S.; Choi, D.; Kwak, J.; Park, C.; Glycobiology 17, 955-962 (2007)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
5.1.3.29
expression in Escherichia coli, cloned into pcDNA3.1 plasmid and transfected into HepG2 cells
Homo sapiens
5.1.3.29
expression in Escherichia coli, cloned into pcDNA3.1 plasmid and transfected into HepG2 cells
Mus musculus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.1.3.29
alpha-L-fucopyranose
Mus musculus
the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway
beta-L-fucopyranose
-
-
r
5.1.3.29
alpha-L-fucopyranose
Homo sapiens
the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway
beta-L-fucopyranose
-
-
r
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.1.3.29
Homo sapiens
A2VDF0
-
-
5.1.3.29
Mus musculus
Q8R2K1
-
-
Purification (Commentary)
EC Number
Commentary
Organism
5.1.3.29
-
Homo sapiens
5.1.3.29
-
Mus musculus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
5.1.3.29
kidney
-
Mus musculus
-
5.1.3.29
liver
-
Mus musculus
-
5.1.3.29
muscle
marginal expression
Mus musculus
-
5.1.3.29
pancreas
-
Mus musculus
-
5.1.3.29
small intestine
-
Mus musculus
-
5.1.3.29
testis
marginal expression
Mus musculus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.1.3.29
alpha-L-fucopyranose
the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway
725106
Mus musculus
beta-L-fucopyranose
-
-
-
r
5.1.3.29
alpha-L-fucopyranose
the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway
725106
Homo sapiens
beta-L-fucopyranose
-
-
-
r
5.1.3.29
alpha-L-fucopyranose
an exchange rate of alpha-to-beta conversion of L-fucose in the absence of FucU is extremely slow
725106
Mus musculus
beta-L-fucopyranose
-
-
-
r
Subunits
EC Number
Subunits
Commentary
Organism
5.1.3.29
More
mainly homodimer, but exists also as homotetramer, homooctamer, and homodecamer. The homodimeric form seems to be catalytically inactive
Mus musculus
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
5.1.3.29
expression in Escherichia coli, cloned into pcDNA3.1 plasmid and transfected into HepG2 cells
Homo sapiens
5.1.3.29
expression in Escherichia coli, cloned into pcDNA3.1 plasmid and transfected into HepG2 cells
Mus musculus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.1.3.29
alpha-L-fucopyranose
Mus musculus
the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway
beta-L-fucopyranose
-
-
r
5.1.3.29
alpha-L-fucopyranose
Homo sapiens
the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway
beta-L-fucopyranose
-
-
r
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
5.1.3.29
-
Homo sapiens
5.1.3.29
-
Mus musculus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
5.1.3.29
kidney
-
Mus musculus
-
5.1.3.29
liver
-
Mus musculus
-
5.1.3.29
muscle
marginal expression
Mus musculus
-
5.1.3.29
pancreas
-
Mus musculus
-
5.1.3.29
small intestine
-
Mus musculus
-
5.1.3.29
testis
marginal expression
Mus musculus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.1.3.29
alpha-L-fucopyranose
the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway
725106
Mus musculus
beta-L-fucopyranose
-
-
-
r
5.1.3.29
alpha-L-fucopyranose
the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway
725106
Homo sapiens
beta-L-fucopyranose
-
-
-
r
5.1.3.29
alpha-L-fucopyranose
an exchange rate of alpha-to-beta conversion of L-fucose in the absence of FucU is extremely slow
725106
Mus musculus
beta-L-fucopyranose
-
-
-
r
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
5.1.3.29
More
mainly homodimer, but exists also as homotetramer, homooctamer, and homodecamer. The homodimeric form seems to be catalytically inactive
Mus musculus
General Information
EC Number
General Information
Commentary
Organism
5.1.3.29
physiological function
the mammalian mutarotase is functional in facilitated incorporation of fucose through the salvage pathway
Homo sapiens
5.1.3.29
physiological function
the mammalian mutarotase is functional in facilitated incorporation of fucose through the salvage pathway
Mus musculus
General Information (protein specific)
EC Number
General Information
Commentary
Organism
5.1.3.29
physiological function
the mammalian mutarotase is functional in facilitated incorporation of fucose through the salvage pathway
Homo sapiens
5.1.3.29
physiological function
the mammalian mutarotase is functional in facilitated incorporation of fucose through the salvage pathway
Mus musculus