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Literature summary extracted from

  • Park, D.; Ryu, K.S.; Choi, D.; Kwak, J.; Park, C.
    Characterization and role of fucose mutarotase in mammalian cells (2007), Glycobiology, 17, 955-962.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.1.3.29 expression in Escherichia coli, cloned into pcDNA3.1 plasmid and transfected into HepG2 cells Mus musculus
5.1.3.29 expression in Escherichia coli, cloned into pcDNA3.1 plasmid and transfected into HepG2 cells Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.1.3.29 alpha-L-fucopyranose Mus musculus the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway beta-L-fucopyranose
-
 r
5.1.3.29 alpha-L-fucopyranose Homo sapiens the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway beta-L-fucopyranose
-
 r

Organism

EC Number Organism UniProt Comment Textmining
5.1.3.29 Homo sapiens A2VDF0
-
-
5.1.3.29 Mus musculus Q8R2K1
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.1.3.29
-
 Mus musculus
5.1.3.29
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.1.3.29 kidney
-
 Mus musculus
-
5.1.3.29 liver
-
 Mus musculus
-
5.1.3.29 muscle marginal expression Mus musculus
-
5.1.3.29 pancreas
-
 Mus musculus
-
5.1.3.29 small intestine
-
 Mus musculus
-
5.1.3.29 testis marginal expression Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.1.3.29 alpha-L-fucopyranose the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway Mus musculus beta-L-fucopyranose
-
 r
5.1.3.29 alpha-L-fucopyranose the enzyme is involved in an interconversion between the two anomeric forms. The enzyme is functional in facilitated incorporation of fucose through the salvage pathway Homo sapiens beta-L-fucopyranose
-
 r
5.1.3.29 alpha-L-fucopyranose an exchange rate of alpha-to-beta conversion of L-fucose in the absence of FucU is extremely slow Mus musculus beta-L-fucopyranose
-
 r

Subunits

EC Number Subunits Comment Organism
5.1.3.29 More mainly homodimer, but exists also as homotetramer, homooctamer, and homodecamer. The homodimeric form seems to be catalytically inactive Mus musculus

Synonyms

EC Number Synonyms Comment Organism
5.1.3.29 FucU
-
 Mus musculus
5.1.3.29 FucU
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
5.1.3.29 physiological function the mammalian mutarotase is functional in facilitated incorporation of fucose through the salvage pathway Mus musculus
5.1.3.29 physiological function the mammalian mutarotase is functional in facilitated incorporation of fucose through the salvage pathway Homo sapiens