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Literature summary extracted from

  • Dammanahalli, J.K.; Duffel, M.W.
    Oxidative modification of rat sulfotransferase 1A1 activity in hepatic tissue slices correlates with effects on the purified enzyme (2012), Drug Metab. Dispos., 40, 298-303.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.8.2.1 Diamide i.e. 1,1'-azobis(N,N-dimethylformamide), diamide significantly increases the sulfation of 7-hydroxycoumarin at an optimal concentration of 0.005 mM Rattus norvegicus
2.8.2.1 tert-butyl hydroperoxide tert-butyl hydroperoxide significantly increases the sulfation of 7-hydroxycoumarin at an optimal concentration of 0.01 mM Rattus norvegicus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.8.2.1 expressed in Escherichia coli BL21(DE3) cells Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.1 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.8.2.1 PAP-agarose affinity chromatography Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.1 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.1 3'-phosphoadenylyl sulfate + 7-hydroxycoumarin
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + 7-hydroxycoumarin sulfate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.8.2.1 sulfotransferase 1A1
-
 Rattus norvegicus
2.8.2.1 SULT1A1
-
 Rattus norvegicus