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Literature summary extracted from

  • Zhang, S.; Wei, T.; Hou, G.; Zhang, C.; Liang, P.; Ni, J.; Sheng, D.; Shen, Y.
    Archaeal DNA helicase HerA interacts with Mre11 homologue and unwinds blunt-ended double-stranded DNA and recombination intermediates (2008), DNA Repair, 7, 380-391.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
5.6.2.3 dsDNA ATPase activity of StoHerA is stimulated by ssDNA and dsDNA Sulfurisphaera tokodaii
5.6.2.3 repair proteins Mre11 stimulates helicase activity Sulfurisphaera tokodaii
5.6.2.3 ssDNA ATPase activity of StoHerA is stimulated by ssDNA and dsDNA Sulfurisphaera tokodaii
5.6.2.4 dsDNA ATPase activity of StoHerA is stimulated by ssDNA and dsDNA Sulfurisphaera tokodaii
5.6.2.4 repair proteins Mre11 stimulates helicase activity Sulfurisphaera tokodaii
5.6.2.4 ssDNA ATPase activity of StoHerA is stimulated by ssDNA and dsDNA Sulfurisphaera tokodaii

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.6.2.3
-
Sulfurisphaera tokodaii
5.6.2.4
-
Sulfurisphaera tokodaii

Protein Variants

EC Number Protein Variants Comment Organism
5.6.2.3 E355A mutation results in loss of ATPase and DNA helicase activities, and also dsDNA-binding ability, indicating that this residue is involved in the coupling of ATP hydrolysis, dsDNA-binding, and helicase activities Sulfurisphaera tokodaii
5.6.2.4 E355A mutation results in loss of ATPase and DNA helicase activities, and also dsDNA-binding ability, indicating that this residue is involved in the coupling of ATP hydrolysis, dsDNA-binding, and helicase activities Sulfurisphaera tokodaii

Organism

EC Number Organism UniProt Comment Textmining
5.6.2.3 Sulfurisphaera tokodaii Q96YR7
-
-
5.6.2.3 Sulfurisphaera tokodaii 7 Q96YR7
-
-
5.6.2.4 Sulfurisphaera tokodaii Q96YR7
-
-
5.6.2.4 Sulfurisphaera tokodaii 7 Q96YR7
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.6.2.3
-
Sulfurisphaera tokodaii
5.6.2.4
-
Sulfurisphaera tokodaii

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.2.3 ATP + H2O the enzyme unwinds Holliday junction, splayed-armDNA, aswell as 5'- or 3'-overhang with high efficiency Sulfurisphaera tokodaii ADP + phosphate
-
?
5.6.2.3 ATP + H2O the enzyme unwinds Holliday junction, splayed-armDNA, aswell as 5'- or 3'-overhang with high efficiency Sulfurisphaera tokodaii 7 ADP + phosphate
-
?
5.6.2.4 ATP + H2O the enzyme unwinds Holliday junction, splayed-armDNA, aswell as 5'- or 3'-overhang with high efficiency Sulfurisphaera tokodaii ADP + phosphate
-
?
5.6.2.4 ATP + H2O the enzyme unwinds Holliday junction, splayed-armDNA, aswell as 5'- or 3'-overhang with high efficiency Sulfurisphaera tokodaii 7 ADP + phosphate
-
?

Synonyms

EC Number Synonyms Comment Organism
5.6.2.3 HerA
-
Sulfurisphaera tokodaii
5.6.2.4 HerA
-
Sulfurisphaera tokodaii

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
5.6.2.3 8
-
assay at Sulfurisphaera tokodaii
5.6.2.4 8
-
assay at Sulfurisphaera tokodaii