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Literature summary extracted from

  • Cao, Y.; Zhao, B.; Han, Y.; Zhang, J.; Li, X.; Qiu, C.; Wu, X.; Hong, Y.; Ai, D.; Lin, J.; Fu, Z.
    Gene gun bombardment with DNA-coated golden particles enhanced the protective effect of a DNA vaccine based on thioredoxin glutathione reductase of Schistosoma japonicum (2013), BioMed Res. Int., 2013, 952416.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.8.1.B1 additional information the recombinant plasmid DNA vaccine pVAX1/SjTGR lowers enzymatic activity in vivo and in vitro Schistosoma japonicum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.1.B1 2 GSH + NADP+ Schistosoma japonicum
-
 GSSG + NADPH + H+
-
 ?
1.8.1.B1 thioredoxin + NADP+ Schistosoma japonicum
-
 thioredoxin disulfide + NADPH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.8.1.B1 Schistosoma japonicum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.1.B1 2 GSH + NADP+
-
 Schistosoma japonicum GSSG + NADPH + H+
-
 ?
1.8.1.B1 5,5'-dithiobis(2-nitrobenzoic acid) + NADPH + H+
-
 Schistosoma japonicum 2-nitro-5-thiobenzoate + NADP+
-
 ?
1.8.1.B1 thioredoxin + NADP+
-
 Schistosoma japonicum thioredoxin disulfide + NADPH + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.8.1.B1 TGR
-
 Schistosoma japonicum

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.1.B1 FAD
-
 Schistosoma japonicum
1.8.1.B1 NADP+
-
 Schistosoma japonicum