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Literature summary extracted from

  • Uno, Y.; Shimizu, M.; Yamazaki, H.
    Molecular and functional characterization of flavin-containing monooxygenases in cynomolgus macaque (2013), Biochem. Pharmacol., 85, 1837-1847.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.14.13.8 65000
-
 x * 65000, SDS-PAGE Macaca fascicularis

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.8 Macaca fascicularis KC734478 isoform FMO1
-
1.14.13.8 Macaca fascicularis KC734481 isoform FMO2
-
1.14.13.8 Macaca fascicularis KC734482 isoform FMO3
-
1.14.13.8 Macaca fascicularis KC734486 isoform FMO5
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.13.8 kidney most abundantly expressed Macaca fascicularis
-
1.14.13.8 liver most abundantly expressed Macaca fascicularis
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.8 benzydamine + NADPH + O2
-
 Macaca fascicularis benzydamine N-oxide + NADP+ + H2O
-
 ?
1.14.13.8 benzydamine + NADPH + O2 highest activity of all isoforms tested Macaca fascicularis benzydamine N-oxide + NADP+ + H2O
-
 ?
1.14.13.8 methimazole + NADPH + H+ + O2
-
 Macaca fascicularis methimazole N-oxide + NADP+ + H2O
-
 ?
1.14.13.8 methimazole + NADPH + H+ + O2 about 25% of the activityy with substrate benzydamine Macaca fascicularis methimazole N-oxide + NADP+ + H2O
-
 ?
1.14.13.8 trimethylamine + NADPH + H+ + O2
-
 Macaca fascicularis trimethylamine N-oxide + NADP+ + H2O
-
 ?

Subunits

EC Number Subunits Comment Organism
1.14.13.8 ? x * 65000, SDS-PAGE Macaca fascicularis