EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.8.1.2 | C247S | inactive | Mus musculus |
2.8.1.2 | R187G | inactive | Mus musculus |
2.8.1.2 | R196G | the mutant shows reduced H2S-producing activity | Mus musculus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.8.1.2 | sulfite | H2S production by the enzyme is suppressed by sulfite | Mus musculus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.8.1.2 | mitochondrion | - |
Mus musculus | 5739 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.8.1.2 | Mus musculus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.8.1.2 | brain | - |
Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.1.2 | 3-mercaptopyruvate + thiosulfate | - |
Mus musculus | pyruvate + H2S | - |
? | |
2.8.1.2 | additional information | the enzyme produces hydrogen sulfide in the presence of both cysteine and 2-oxoglutarate. Thioredoxin and dihydrolipoic acid associate with 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide. Other reducing substances, such as NADPH, NADH, GSH, cysteine and CoA, do not have any effect on the reaction | Mus musculus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.8.1.2 | 3MST | - |
Mus musculus |