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Literature summary extracted from

  • Queiroz, R.F.; Vaz, S.M.; Augusto, O.
    Inhibition of the chlorinating activity of myeloperoxidase by tempol: revisiting the kinetics and mechanisms (2011), Biochem. J., 439, 423-431.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.11.2.2 4-hydroxy-2,2,6,6-tetramethyl piperidine-1-oxyl i.e. tempol, inhibits both H2O2 consumption and taurine chlorination, reacts mostly as a reversible inhibitor of MPO by trapping it as MPO-II and the MPO-II-tempol complex, which are not within the chlorinating cycle Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.11.2.2 Homo sapiens P05164
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.11.2.2 commercial preparation
-
Homo sapiens
-
1.11.2.2 leukocyte
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.2.2 taurine + Cl- + H2O2
-
Homo sapiens taurine chloramine + H2O
-
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