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Literature summary extracted from

  • Jeon, H.B.; Jang, Y.
    Reversible inactivation of bovine plasma amine oxidase by cysteamine and related analogs (2010), Biochem. Biophys. Res. Commun., 403, 442-446.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.21 2-(methylamino)ethanethiol reversible inhibition Bos taurus
1.4.3.21 2-(methylthio)ethylamine weak irreversible inhibitor Bos taurus
1.4.3.21 3-aminopropanethiol reversible inhibition Bos taurus
1.4.3.21 cysteamine reversible inhibition Bos taurus
1.4.3.21 additional information not inhibited by 2-aminoethanol and 2-(N,N-dimethylamino)ethanethiol Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.21 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.21 plasma
-
Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.21 benzylamine + H2O + O2
-
Bos taurus benzaldehyde + NH3 + H2O2
-
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Synonyms

EC Number Synonyms Comment Organism
1.4.3.21 EC 1.4.3.6 formerly Bos taurus
1.4.3.21 PAO
-
Bos taurus
1.4.3.21 quinone-dependent amine oxidase
-
Bos taurus

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.3.21 2,4,5-trihydroxyphenylalanine quinone
-
Bos taurus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.4.3.21 0.0125
-
in 100 mM potassium phosphate buffer, pH 7.2, at 30°C Bos taurus cysteamine
1.4.3.21 0.3
-
in 100 mM potassium phosphate buffer, pH 7.2, at 30°C Bos taurus 3-aminopropanethiol
1.4.3.21 1.3
-
in 100 mM potassium phosphate buffer, pH 7.2, at 30°C Bos taurus 2-(methylthio)ethylamine
1.4.3.21 5
-
in 100 mM potassium phosphate buffer, pH 7.2, at 30°C Bos taurus 2-(methylamino)ethanethiol