Data extracted from this reference:
Activating Compound
2.4.2.12
ATP
essential activator
Homo sapiens
Cloned(Commentary)
KM Value [mM]
2.4.2.12
0.00051
5-phosphoribosyl 1-diphosphate
with 1 mM ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.00122
nicotinamide
with 1 mM ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.00806
nicotinamide
without ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.0232
5-phosphoribosyl 1-diphosphate
without ATP, pH 7.5, 37°C
Homo sapiens
Organism
Specific Activity [micromol/min/mg]
2.4.2.12
0.00213
at 0.001 mM 5-phosphoribosyl 1-diphosphate, without ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.0259
at 0.050 mM 5-phosphoribosyl 1-diphosphate, without ATP, pH 7.5, 37°C; substrate 5-phosphoribosyl 1-diphosphate, without ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.0393
substrate nicotinamide, without ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.0397
substrate nicotinamide, with 1 mM ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.0481
at 0.050 mM 5-phosphoribosyl 1-diphosphate, with 1 mM ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.0704
at 0.001 mM 5-phosphoribosyl 1-diphosphate, with 1 mM ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.0741
substrate 5-phosphoribosyl 1-diphosphate, with 1 mM ATP, pH 7.5, 37°C
Homo sapiens
Substrates and Products (Substrate)
2.4.2.12
nicotinamide + 5-phosphoribosyl 1-diphosphate
723535
Homo sapiens
nicotinamide mononucleotide + diphosphate
?
Synonyms
2.4.2.12
nicotinamide phosphoribosyltransferase
Homo sapiens
2.4.2.12
nicotinamide phosphoribosyltransferase/Visfatin
does not catalyze nicotinamide mononucleotide formation in blood plasma
Homo sapiens
Activating Compound (protein specific)
2.4.2.12
ATP
essential activator
Homo sapiens
Cloned(Commentary) (protein specific)
KM Value [mM] (protein specific)
2.4.2.12
0.00051
5-phosphoribosyl 1-diphosphate
with 1 mM ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.00122
nicotinamide
with 1 mM ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.00806
nicotinamide
without ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.0232
5-phosphoribosyl 1-diphosphate
without ATP, pH 7.5, 37°C
Homo sapiens
Specific Activity [micromol/min/mg] (protein specific)
2.4.2.12
0.00213
at 0.001 mM 5-phosphoribosyl 1-diphosphate, without ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.0259
at 0.050 mM 5-phosphoribosyl 1-diphosphate, without ATP, pH 7.5, 37°C; substrate 5-phosphoribosyl 1-diphosphate, without ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.0393
substrate nicotinamide, without ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.0397
substrate nicotinamide, with 1 mM ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.0481
at 0.050 mM 5-phosphoribosyl 1-diphosphate, with 1 mM ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.0704
at 0.001 mM 5-phosphoribosyl 1-diphosphate, with 1 mM ATP, pH 7.5, 37°C
Homo sapiens
2.4.2.12
0.0741
substrate 5-phosphoribosyl 1-diphosphate, with 1 mM ATP, pH 7.5, 37°C
Homo sapiens
Substrates and Products (Substrate) (protein specific)
2.4.2.12
nicotinamide + 5-phosphoribosyl 1-diphosphate
723535
Homo sapiens
nicotinamide mononucleotide + diphosphate
?