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Literature summary extracted from

  • Byrne, E.H.; Prosser, I.; Muttucumaru, N.; Curtis, T.Y.; Wingler, A.; Powers, S.; Halford, N.G.
    Overexpression of GCN2-type protein kinase in wheat has profound effects on free amino acid concentration and gene expression (2012), Plant Biotechnol. J., 10, 328-340.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.7.11.20 agriculture manipulation of TaGCN2 gene expression can be used to reduce free asparagine accumulation in wheat grain and the risk of acrylamide formation in wheat products Triticum aestivum

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.20 overexpression in transgenic wheat results in significant decreases in total free amino acid concentration in the grain, with free asparagine concentration in particular being much lower than in controls Triticum aestivum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.20 ATP + [elongation factor 2] Triticum aestivum the phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 is a key point of regulation of protein synthesis and amino acid homoeostasis in eukaryotes ADP + [elongation factor 2] phosphate
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Organism

EC Number Organism UniProt Comment Textmining
2.7.11.20 Triticum aestivum
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-
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.20 ATP + [elongation factor 2]
-
 Triticum aestivum ADP + [elongation factor 2] phosphate
-
 ?
2.7.11.20 ATP + [elongation factor 2] the phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 is a key point of regulation of protein synthesis and amino acid homoeostasis in eukaryotes Triticum aestivum ADP + [elongation factor 2] phosphate
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 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.20 TaGCN2
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 Triticum aestivum

General Information

EC Number General Information Comment Organism
2.7.11.20 physiological function the enzyme plays an important role in the regulation of genes encoding enzymes of amino acid biosynthesis in wheat. The enzyme is implicated in sulfur signalling Triticum aestivum