EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.5.1.39 | 4-nitrobenzoate | competitive enzyme inhibition, cell treatement with 4-nitrobenzoate leads to a decrease in coenzyme Q content, but 4-nitrobenzoate treatment has no apparent toxic effect on the cells and does not decrease Q concentration by inducing oxidative stress | Mus musculus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.5.1.39 | mitochondrial membrane | - |
Mus musculus | 31966 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.5.1.39 | a polyprenyl diphosphate + 4-hydroxybenzoate | Mus musculus | - |
diphosphate + a 4-hydroxy-3-polyprenylbenzoate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.5.1.39 | Mus musculus | - |
gene COQ2 | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.5.1.39 | fibroblast | - |
Mus musculus | - |
2.5.1.39 | Swiss-3T3 cell | - |
Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.5.1.39 | a polyprenyl diphosphate + 4-hydroxybenzoate | - |
Mus musculus | diphosphate + a 4-hydroxy-3-polyprenylbenzoate | - |
? | |
2.5.1.39 | a polyprenyl diphosphate + 4-hydroxybenzoate | Coq2 is quite unspecific with regard to its substrates | Mus musculus | diphosphate + a 4-hydroxy-3-polyprenylbenzoate | - |
? | |
2.5.1.39 | geranyl diphosphate + 4-hydroxybenzoate | - |
Mus musculus | diphosphate + 3-geranyl-4-hydroxybenzoate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.5.1.39 | 4-hydroxybenzoate:polyprenyl transferase | - |
Mus musculus |
2.5.1.39 | COQ2 | - |
Mus musculus |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.5.1.39 | physiological function | Coq2 plays an important role in coenzyme Q metabolism | Mus musculus |