EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.4.1.109 | D77A | the PMT1 mutant shows 71.95% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | D77A/E78A | the PMT1 mutant shows 0.19% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | D77A/E78A | the PMT1 mutant shows 3.59% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | D77A/E78A/D92A/E93A | the PMT1/PMT2 mutant shows 0.24% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | D80A | the PMT4 mutant shows 3.21% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | D80E | the PMT4 mutant shows 52.98% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | D80E/E81D | the PMT4 mutant shows 116.54% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | D92A/E93A | the PMT2 mutant shows 3.63% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | D96A | the PMT1 mutant shows 63.21% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | E78A | the PMT1 mutant shows 46.68% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | E81A | the PMT4 mutant shows 1.43% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | E81D | the PMT4 mutant shows 46.59% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | F76A | the PMT1 mutant shows 78.79% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | F81A | the PMT1 mutant shows 71.71% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | H80A | the PMT1 mutant shows 83.03% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | H98A | the PMT1 mutant shows 62.77% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | P100A | the PMT1 mutant shows 59.67% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | P99A | the PMT1 mutant shows 61.77% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | V97A | the PMT1 mutant shows 80.23% activity compared to the wild type enzyme | Homo sapiens |
2.4.1.109 | Y88A | the PMT1 mutant shows 73.79% activity compared to the wild type enzyme | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.4.1.109 | endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
2.4.1.109 | membrane | a membrane protein | Homo sapiens | 16020 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.4.1.109 | 88000 | - |
x * 88000, Pmt2p | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.109 | Homo sapiens | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.109 | dolichyl phosphate D-mannose + N-acetyl-SSSSS | worst substrate | Homo sapiens | dolichyl phosphate + O-D-mannosyl-N-acetyl-SSSSS | - |
? | |
2.4.1.109 | dolichyl phosphate D-mannose + N-acetyl-YASAV | - |
Homo sapiens | dolichyl phosphate + O-D-mannosyl-N-acetyl-YASAV | - |
? | |
2.4.1.109 | dolichyl phosphate D-mannose + N-acetyl-YATAV | best substrate | Homo sapiens | dolichyl phosphate + O-D-mannosyl-N-acetyl-YATAV | - |
? | |
2.4.1.109 | dolichyl phosphate D-mannose + N-acetyl-YATAVK-biotin | N-acetyl-YATAVK-biotin preferentially reacts with isoform Pmt1p | Homo sapiens | dolichyl phosphate + O-D-mannosyl-N-acetyl-YATAVK-biotin | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.4.1.109 | ? | x * 88000, Pmt2p | Homo sapiens |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.1.109 | dolichyl-phosphate-mannose-protein mannosyltransferase 1 | - |
Homo sapiens |
2.4.1.109 | PMT | - |
Homo sapiens |
2.4.1.109 | Pmt1p-Pmt2p | - |
Homo sapiens |
2.4.1.109 | Pmt4p | - |
Homo sapiens |