EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.21 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.1.21 | H-1299 cell | - |
Homo sapiens | - |
2.7.1.21 | HCT-116 cell | - |
Homo sapiens | - |
2.7.1.21 | SW-480 cell | - |
Homo sapiens | - |
2.7.1.21 | U2-OS cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.21 | ATP + thymidine | - |
Homo sapiens | ADP + dTMP | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.21 | thymidine kinase 1 | - |
Homo sapiens |
2.7.1.21 | TK1 | - |
Homo sapiens |
EC Number | Organism | Comment | Expression |
---|---|---|---|
2.7.1.21 | Homo sapiens | DNA damage causes up-regulation of thymidine kinase 1 in tumor cells | up |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.7.1.21 | malfunction | depletion of thymidine kinase 1 decreases the efficiency of DNA repair during recovery from DNA damage and generates more cell death | Homo sapiens |
2.7.1.21 | physiological function | thymidine kinase 1 C´contributes to the increase in dTTP pool during recovery from DNA damage and affects the efficiency of DNA repair during recovery for G2/M progression | Homo sapiens |