Literature summary extracted from
Jansson, A.; Koskiniemi, H.; Mäntsälä, P.; Niemi, J.; Schneider, G.
Crystal structure of a ternary complex of DnrK, a methyltransferase in daunorubicin biosynthesis, with bound products (2004), J. Biol. Chem., 279, 41149-41156.
Cloned(Commentary)
EC Number |
Cloned (Comment) |
Organism |
---|
2.1.1.292 |
- |
Streptomyces peucetius |
Crystallization (Commentary)
EC Number |
Crystallization (Comment) |
Organism |
---|
2.1.1.292 |
the crystal structure of the ternary complex of this enzyme with the bound products S-adenosyl-L-homocysteine and 4-methoxy-epsilon-rhodomycin T is determined to a 2.35 A resolution, vapor diffusion method at 20°C |
Streptomyces peucetius |
Protein Variants
EC Number |
Protein Variants |
Comment |
Organism |
---|
2.1.1.292 |
Y142W |
48% of the rate of the recombinant native enzyme with 4-methoxy-epsilon-rhodomycin T |
Streptomyces peucetius |
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
2.1.1.292 |
Streptomyces peucetius |
Q06528 |
- |
- |
Purification (Commentary)
EC Number |
Purification (Comment) |
Organism |
---|
2.1.1.292 |
- |
Streptomyces peucetius |
Subunits
EC Number |
Subunits |
Comment |
Organism |
---|
2.1.1.292 |
homodimer |
- |
Streptomyces peucetius |
Synonyms
EC Number |
Synonyms |
Comment |
Organism |
---|
2.1.1.292 |
DnrK |
- |
Streptomyces peucetius |
General Information
EC Number |
General Information |
Comment |
Organism |
---|
2.1.1.292 |
physiological function |
the enzyme is involved in daunorubicin biosynthesis |
Streptomyces peucetius |