EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.1.36 | expression in Escherichia coli | Saccharolobus solfataricus |
2.7.4.2 | expression in Escherichia coli | Saccharolobus solfataricus |
4.1.1.33 | expression in Escherichia coli | Saccharolobus solfataricus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.7.1.36 | 37000 | - |
x * 37000, calculated from sequence | Saccharolobus solfataricus |
2.7.4.2 | 36200 | - |
x * 36200, calculated from sequence | Saccharolobus solfataricus |
4.1.1.33 | 37000 | - |
x * 37000, calculated | Saccharolobus solfataricus |
4.1.1.33 | 37028 | - |
x * 37028, calculated from sequence | Saccharolobus solfataricus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.36 | additional information | Saccharolobus solfataricus | the enzyme is involved in the modified mevalonate pathway. The recombinant protein is active. However in vitro conversion of the intermediates in the classical and modified pathways by cell-free extract from Sulfolobus solfataricus indicates that only the classical pathway likely works in the organism | ? | - |
? | |
2.7.1.36 | additional information | Saccharolobus solfataricus P2 | the enzyme is involved in the modified mevalonate pathway. The recombinant protein is active. However in vitro conversion of the intermediates in the classical and modified pathways by cell-free extract from Sulfolobus solfataricus indicates that only the classical pathway likely works in the organism | ? | - |
? | |
2.7.4.2 | ATP + (R)-5-phosphomevalonate | Saccharolobus solfataricus | the enzyme is involved in the classical mevalonate pathway | ADP + (R)-5-diphosphomevalonate | - |
? | |
2.7.4.2 | ATP + (R)-5-phosphomevalonate | Saccharolobus solfataricus P2 | the enzyme is involved in the classical mevalonate pathway | ADP + (R)-5-diphosphomevalonate | - |
? | |
4.1.1.33 | ATP + (R)-5-diphosphomevalonate | Saccharolobus solfataricus | the enzyme catalyzes a reaction of the classical mevalonate pathway | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
4.1.1.33 | ATP + (R)-5-diphosphomevalonate | Saccharolobus solfataricus P2 | the enzyme catalyzes a reaction of the classical mevalonate pathway | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
4.1.1.33 | ATP + (R)-5-diphosphomevalonate | Saccharolobus solfataricus DSM 1617 | the enzyme catalyzes a reaction of the classical mevalonate pathway | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.36 | Saccharolobus solfataricus | Q980D2 | - |
- |
2.7.1.36 | Saccharolobus solfataricus P2 | Q980D2 | - |
- |
2.7.4.2 | Saccharolobus solfataricus | Q97UL6 | - |
- |
2.7.4.2 | Saccharolobus solfataricus P2 | Q97UL6 | - |
- |
4.1.1.33 | Saccharolobus solfataricus | Q97UL5 | - |
- |
4.1.1.33 | Saccharolobus solfataricus DSM 1617 | Q97UL5 | - |
- |
4.1.1.33 | Saccharolobus solfataricus P2 | Q97UL5 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.1.36 | - |
Saccharolobus solfataricus |
2.7.4.2 | - |
Saccharolobus solfataricus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.36 | ATP + (R)-mevalonate | the enzyme is involved in the modified mevalonate pathway. The recombinant protein is active. However in vitro conversion of the intermediates in the classical and modified pathways by cell-free extract from Sulfolobus solfataricus indicates that only the classical pathway likely works in the organism | Saccharolobus solfataricus | ADP + (R)-5-phosphomevalonate | - |
? | |
2.7.1.36 | ATP + (R)-mevalonate | the enzyme is involved in the modified mevalonate pathway. The recombinant protein is active. However in vitro conversion of the intermediates in the classical and modified pathways by cell-free extract from Sulfolobus solfataricus indicates that only the classical pathway likely works in the organism | Saccharolobus solfataricus P2 | ADP + (R)-5-phosphomevalonate | - |
? | |
2.7.1.36 | additional information | the enzyme is involved in the modified mevalonate pathway. The recombinant protein is active. However in vitro conversion of the intermediates in the classical and modified pathways by cell-free extract from Sulfolobus solfataricus indicates that only the classical pathway likely works in the organism | Saccharolobus solfataricus | ? | - |
? | |
2.7.1.36 | additional information | the enzyme is involved in the modified mevalonate pathway. The recombinant protein is active. However in vitro conversion of the intermediates in the classical and modified pathways by cell-free extract from Sulfolobus solfataricus indicates that only the classical pathway likely works in the organism | Saccharolobus solfataricus P2 | ? | - |
? | |
2.7.4.2 | ATP + (R)-5-phosphomevalonate | - |
Saccharolobus solfataricus | ADP + (R)-5-diphosphomevalonate | - |
? | |
2.7.4.2 | ATP + (R)-5-phosphomevalonate | the enzyme is involved in the classical mevalonate pathway | Saccharolobus solfataricus | ADP + (R)-5-diphosphomevalonate | - |
? | |
2.7.4.2 | ATP + (R)-5-phosphomevalonate | - |
Saccharolobus solfataricus P2 | ADP + (R)-5-diphosphomevalonate | - |
? | |
2.7.4.2 | ATP + (R)-5-phosphomevalonate | the enzyme is involved in the classical mevalonate pathway | Saccharolobus solfataricus P2 | ADP + (R)-5-diphosphomevalonate | - |
? | |
4.1.1.33 | ATP + (R)-5-diphosphomevalonate | - |
Saccharolobus solfataricus | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
4.1.1.33 | ATP + (R)-5-diphosphomevalonate | the enzyme catalyzes a reaction of the classical mevalonate pathway | Saccharolobus solfataricus | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
4.1.1.33 | ATP + (R)-5-diphosphomevalonate | - |
Saccharolobus solfataricus P2 | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
4.1.1.33 | ATP + (R)-5-diphosphomevalonate | the enzyme catalyzes a reaction of the classical mevalonate pathway | Saccharolobus solfataricus P2 | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
4.1.1.33 | ATP + (R)-5-diphosphomevalonate | - |
Saccharolobus solfataricus DSM 1617 | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
4.1.1.33 | ATP + (R)-5-diphosphomevalonate | the enzyme catalyzes a reaction of the classical mevalonate pathway | Saccharolobus solfataricus DSM 1617 | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
4.1.1.33 | additional information | no substrate: mevalonate 5-phosphate | Saccharolobus solfataricus | ? | - |
? | |
4.1.1.33 | additional information | no substrate: mevalonate 5-phosphate | Saccharolobus solfataricus P2 | ? | - |
? | |
4.1.1.33 | additional information | no substrate: mevalonate 5-phosphate | Saccharolobus solfataricus DSM 1617 | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.7.1.36 | ? | x * 37000, calculated from sequence | Saccharolobus solfataricus |
2.7.4.2 | ? | x * 36200, calculated from sequence | Saccharolobus solfataricus |
4.1.1.33 | ? | x * 37000, calculated | Saccharolobus solfataricus |
4.1.1.33 | ? | x * 37028, calculated from sequence | Saccharolobus solfataricus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.36 | MVK | - |
Saccharolobus solfataricus |
2.7.1.36 | SSO0383 | - |
Saccharolobus solfataricus |
2.7.4.2 | PMK | - |
Saccharolobus solfataricus |
2.7.4.2 | SSO2988 | - |
Saccharolobus solfataricus |
4.1.1.33 | DMD | - |
Saccharolobus solfataricus |
4.1.1.33 | SSO2989 | - |
Saccharolobus solfataricus |
4.1.1.33 | SSO2989 | locus name | Saccharolobus solfataricus |
EC Number | General Information | Comment | Organism |
---|---|---|---|
4.1.1.33 | metabolism | the enzyme catalyzes a reaction of the classical mevalonate pathway | Saccharolobus solfataricus |