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Literature summary extracted from

  • Hove-Jensen, B.; McSorley, F.R.; Zechel, D.L.
    Physiological role of phnP-specified phosphoribosyl cyclic phosphodiesterase in catabolism of organophosphonic acids by the carbon-phosphorus lyase pathway (2011), J. Am. Chem. Soc., 133, 3617-3624.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.7.1.1 alpha-D-ribose 1-methylphosphonate 5-phosphate Escherichia coli
-
 alpha-D-ribose 1,2-cyclic-phosphate 5-phosphate + methane
-
 ?
4.7.1.1 alpha-D-ribose 1-methylphosphonate 5-phosphate Escherichia coli HO2536
-
 alpha-D-ribose 1,2-cyclic-phosphate 5-phosphate + methane
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.55 Escherichia coli
-
-
-
4.7.1.1 Escherichia coli
-
-
-
4.7.1.1 Escherichia coli HO2536
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.55 5-phospho-alpha-D-ribose 1,2-cyclic phosphate + H2O
-
 Escherichia coli alpha-D-ribose 1,5-bisphosphate enzyme PhnP regiospecifically converts 5-phospho-alpha-D-ribosyl 1,2-cyclic to alpha-D-ribosyl 1,5-bisphosphate ?
3.1.4.55 5-phospho-alpha-D-ribose 1,2-cyclic phosphate + H2O
-
 Escherichia coli HO2536 alpha-D-ribose 1,5-bisphosphate enzyme PhnP regiospecifically converts 5-phospho-alpha-D-ribosyl 1,2-cyclic to alpha-D-ribosyl 1,5-bisphosphate ?
3.1.4.55 alpha-D-ribosyl 1,2-cyclic phosphate + H2O enzyme PhnP regiospecifically converts alpha-D-ribosyl 1,2-cyclic phosphate to alpha-D-ribosyl 1-phosphate Escherichia coli alpha-D-ribosyl 1-phosphate
-
 ?
3.1.4.55 alpha-D-ribosyl 1,2-cyclic phosphate + H2O enzyme PhnP regiospecifically converts alpha-D-ribosyl 1,2-cyclic phosphate to alpha-D-ribosyl 1-phosphate Escherichia coli HO2536 alpha-D-ribosyl 1-phosphate
-
 ?
4.7.1.1 alpha-D-ribose 1-methylphosphonate 5-phosphate
-
 Escherichia coli alpha-D-ribose 1,2-cyclic-phosphate 5-phosphate + methane
-
 ?
4.7.1.1 alpha-D-ribose 1-methylphosphonate 5-phosphate
-
 Escherichia coli HO2536 alpha-D-ribose 1,2-cyclic-phosphate 5-phosphate + methane
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.7.1.1 phnJ
-
 Escherichia coli

General Information

EC Number General Information Comment Organism
3.1.4.55 physiological function mutants grown in the presence of alkylphosphonic acid or phosphite display the accumulation of alpha-D-ribosyl 1,2-cyclic phosphate and alpha-D-ribosyl 1-alkylphosphonate Escherichia coli