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Literature summary extracted from

  • Hassan, A.E.; Abou-Elkhair, R.A.; Riordan, J.M.; Allan, P.W.; Parker, W.B.; Khare, R.; Waud, W.R.; Montgomery, J.A.; Secrist, J.A.
    Synthesis and evaluation of the substrate activity of C-6 substituted purine ribosides with E. coli purine nucleoside phosphorylase: palladium mediated cross-coupling of organozinc halides with 6-chloropurine nucleosides (2012), Eur. J. Med. Chem., 47, 167-174.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.1 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.1 6-(2-thienyl)-9-(beta-D-ribofuranosyl)purine + phosphate
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 Escherichia coli 6-(2-thienyl)purine + alpha-D-ribose 1-phosphate
-
 ?
2.4.2.1 6-cyclopropyl-9-(beta-D-ribofuranosyl)purine + phosphate
-
 Escherichia coli 6-cyclopropylpurine + alpha-D-ribose 1-phosphate
-
 ?
2.4.2.1 6-ethyl-9-(beta-D-ribofuranosyl)purine + phosphate
-
 Escherichia coli 6-ethylpurine + alpha-D-ribose 1-phosphate
-
 ?
2.4.2.1 6-phenyl-9-(beta-D-ribofuranosyl)purine + phosphate
-
 Escherichia coli 6-phenylpurine + alpha-D-ribose 1-phosphate
-
 ?
2.4.2.1 additional information enzyme shows a high tolerance to the steric and hydrophobic environment at the 6-position of the synthesized purine ribonucleosides Escherichia coli ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.2.1 PNP
-
 Escherichia coli