BRENDA - Enzyme Database

Characterisation of a novel glycosylphosphatidylinositol-anchored mono-ADP-ribosyltransferase isoform in ovary cells

Stilla, A.; Di Paola, S.; Dani, N.; Krebs, C.; Arrizza, A.; Corda, D.; Haag, F.; Koch-Nolte, F.; Di Girolamo, M.; Eur. J. Cell Biol. 90, 665-677 (2011)

Data extracted from this reference:

Engineering
EC Number
Amino acid exchange
Commentary
Organism
2.4.2.31
E207G/E209G
abolished ADP-ribosyltransferase activity. Mutated protein localises to the plasma membrane
Cricetulus griseus
2.4.2.31
E209G
single point mutant of cARTC2.1 cannot hydrolyse NAD+, although it retains low arginine-specific ADP-ribosyltransferase activity. Mutated protein localises to the plasma membrane
Cricetulus griseus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.4.2.31
plasma membrane
-
Cricetulus griseus
5886
-
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.4.2.31
31000
-
calculated from cDNA
Cricetulus griseus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.4.2.31
Cricetulus griseus
-
-
-
Posttranslational Modification
EC Number
Posttranslational Modification
Commentary
Organism
2.4.2.31
additional information
enzyme is glycosylphosphatidylinositol (GPI)-anchored
Cricetulus griseus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.4.2.31
CHO cell
-
Cricetulus griseus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.4.2.31
agmatine + NAD+
-
722180
Cricetulus griseus
nicotinamide + ?
-
-
-
?
Temperature Optimum [°C]
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
2.4.2.31
37
-
assay at
Cricetulus griseus
Engineering (protein specific)
EC Number
Amino acid exchange
Commentary
Organism
2.4.2.31
E207G/E209G
abolished ADP-ribosyltransferase activity. Mutated protein localises to the plasma membrane
Cricetulus griseus
2.4.2.31
E209G
single point mutant of cARTC2.1 cannot hydrolyse NAD+, although it retains low arginine-specific ADP-ribosyltransferase activity. Mutated protein localises to the plasma membrane
Cricetulus griseus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.4.2.31
plasma membrane
-
Cricetulus griseus
5886
-
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.4.2.31
31000
-
calculated from cDNA
Cricetulus griseus
Posttranslational Modification (protein specific)
EC Number
Posttranslational Modification
Commentary
Organism
2.4.2.31
additional information
enzyme is glycosylphosphatidylinositol (GPI)-anchored
Cricetulus griseus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.4.2.31
CHO cell
-
Cricetulus griseus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.4.2.31
agmatine + NAD+
-
722180
Cricetulus griseus
nicotinamide + ?
-
-
-
?
Temperature Optimum [°C] (protein specific)
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
2.4.2.31
37
-
assay at
Cricetulus griseus