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Literature summary extracted from

  • Coker, H.A.; Petersen-Mahrt, S.K.
    The nuclear DNA deaminase AID functions distributively whereas cytoplasmic APOBEC3G has a processive mode of action (2006), DNA Repair, 6, 235-243.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.4.B9
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.5.4.B9 cytoplasm
-
 Homo sapiens 5737
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.4.B9 cytosine in single-stranded viral DNA + H2O Homo sapiens in vitro, the enzyme has a preferred sequence motif of T/CCC and shows a 3'->5' like processivity uracil in single-stranded viral DNA + NH3
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.4.B9 Homo sapiens Q9HC16
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.4.B9
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.4.B9 cytosine in single-stranded viral DNA + H2O in vitro, the enzyme has a preferred sequence motif of T/CCC and shows a 3'->5' like processivity Homo sapiens uracil in single-stranded viral DNA + NH3
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.4.B9 APOBEC3G
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
3.5.4.B9 physiological function the enzyme inhibits HIV replication and inhibits retroviral infection by deaminating first strand cDNA, generating viral DNA mutations and potential viral elimination Homo sapiens