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Literature summary extracted from

  • Fournier-Level, A.; Hugueney, P.; Verries, C.; This, P.; Ageorges, A.
    Genetic mechanisms underlying the methylation level of anthocyanins in grape (Vitis vinifera L.) (2011), BMC Plant Biol., 11, 179.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.1.1.267 genes AOMT2, AOMT3, and AOMT1, DNA and amino acid sequence determination and analysis, expression analysis, association mapping with VvAOMT1 and VvAOMT2 and methylated anthocyanin profiles, overview Vitis vinifera

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.267 S-adenosyl-L-methionine + cyanidin 3-O-beta-D-glucoside Vitis vinifera
-
 S-adenosyl-L-homocysteine + peonidin 3-O-beta-D-glucoside + H+
-
 ?
2.1.1.267 S-adenosyl-L-methionine + delphinidin 3-O-glucoside Vitis vinifera
-
 S-adenosyl-L-homocysteine + petunidin 3-O-beta-D-glucoside
-
 ?
2.1.1.267 S-adenosyl-L-methionine + petunidin 3-O-beta-D-glucoside Vitis vinifera
-
 S-adenosyl-L-homocysteine + malvidin 3-O-beta-D-glucoside
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.267 Vitis vinifera G0YKW8 Syrah x Grenache progeny, 32 unrelated cultivars
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.267 fruit ratio of methylated/non-methylated anthocyanins in berry skin of 32 unrelated cultivars, overview Vitis vinifera
-
2.1.1.267 root hair quantitative real-time PCR expression profiling of AOMT and AOMT2 in hairy roots, overview Vitis vinifera
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.267 S-adenosyl-L-methionine + cyanidin 3-O-beta-D-glucoside
-
 Vitis vinifera S-adenosyl-L-homocysteine + peonidin 3-O-beta-D-glucoside + H+
-
 ?
2.1.1.267 S-adenosyl-L-methionine + delphinidin 3-O-glucoside
-
 Vitis vinifera S-adenosyl-L-homocysteine + petunidin 3-O-beta-D-glucoside
-
 ?
2.1.1.267 S-adenosyl-L-methionine + petunidin 3-O-beta-D-glucoside
-
 Vitis vinifera S-adenosyl-L-homocysteine + malvidin 3-O-beta-D-glucoside
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.267 AOMT
-
 Vitis vinifera
2.1.1.267 AOMT1
-
 Vitis vinifera
2.1.1.267 AOMT2
-
 Vitis vinifera
2.1.1.267 AOMT3
-
 Vitis vinifera

Cofactor

EC Number Cofactor Comment Organism Structure
2.1.1.267 S-adenosyl-L-methionine
-
 Vitis vinifera

General Information

EC Number General Information Comment Organism
2.1.1.267 evolution the VvAOMT genes cluster results from gene duplication Vitis vinifera
2.1.1.267 malfunction the AOMT2 gene presents two SNPs associated with methylation level. These mutations, probably leading to a structural change of the AOMT2 protein, significantly affect the enzyme specific catalytic efficiency for the 3'-O-methylation of delphinidin 3-O-beta-D-glucoside Vitis vinifera
2.1.1.267 additional information ratio of methylated/non-methylated anthocyanins in berry skin of 32 unrelated cultivars, QTL mapping of anthocyanin methylation level, overview Vitis vinifera
2.1.1.267 physiological function VvAOMT2 expression has no direct regulatory effect on anthocyanin methylation, transcriptional regulation of AOMTs and effects on anthocyanin methylation patterns, overview Vitis vinifera