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Literature summary extracted from

  • Cook, P.D.; Holden, H.M.
    GDP-perosamine synthase: structural analysis and production of a novel trideoxysugar (2008), Biochemistry, 47, 2833-2840.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.6.1.102 the three-dimensional structure of the enzyme is determined to a nominal resolution of 1.8 A and refined to an R-factor of 17.9%. Each subunit of the dimeric enzyme contains a seven-stranded mixed beta-sheet, a two-stranded antiparallel beta-sheet, and 12 alpha-helices Caulobacter vibrioides

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.102 GDP-4-dehydro-6-deoxy-alpha-D-mannose + L-glutamate Caulobacter vibrioides
-
 GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-oxoglutarate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.102 Caulobacter vibrioides Q9A9H3
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.102 GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + L-glutamate
-
 Caulobacter vibrioides GDP-4-amino-3,4,6-trideoxy-alpha-D-mannose + 2-oxoglutarate
-
 ?
2.6.1.102 GDP-4-dehydro-6-deoxy-alpha-D-mannose + L-glutamate
-
 Caulobacter vibrioides GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-oxoglutarate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.6.1.102 dimer
-
 Caulobacter vibrioides

Cofactor

EC Number Cofactor Comment Organism Structure
2.6.1.102 pyridoxal 5'-phosphate a pyridoxal-phosphate protein Caulobacter vibrioides