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Literature summary extracted from

  • Trail, F.; Chang, P.K.; Cary, J.; Linz, J.E.
    Structural and functional analysis of the nor-1 gene involved in the biosynthesis of aflatoxins by Aspergillus parasiticus (1994), Appl. Environ. Microbiol., 60, 4078-4085.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.B25
-
 Aspergillus parasiticus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.349 norsolorinic acid + NADPH + H+ Aspergillus parasiticus
-
 (1'S)-averantin + NADP+
-
 ?
1.1.1.349 norsolorinic acid + NADPH + H+ Aspergillus parasiticus NRRL 5862
-
 (1'S)-averantin + NADP+
-
 ?
1.1.1.349 norsolorinic acid + NADPH + H+ Aspergillus parasiticus SU-1
-
 (1'S)-averantin + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.B25 Aspergillus parasiticus Q00278
-
-
1.1.1.B25 Aspergillus parasiticus SU-1 Q00278
-
-
1.1.1.349 Aspergillus parasiticus Q00278
-
-
1.1.1.349 Aspergillus parasiticus NRRL 5862 Q00278
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.349 norsolorinic acid + NADPH + H+
-
 Aspergillus parasiticus (1'S)-averantin + NADP+
-
 ?
1.1.1.349 norsolorinic acid + NADPH + H+
-
 Aspergillus parasiticus NRRL 5862 (1'S)-averantin + NADP+
-
 ?
1.1.1.349 norsolorinic acid + NADPH + H+
-
 Aspergillus parasiticus SU-1 (1'S)-averantin + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.B25 nor-1
-
 Aspergillus parasiticus
1.1.1.349 nor-I
-
 Aspergillus parasiticus

General Information

EC Number General Information Comment Organism
1.1.1.349 malfunction inactivation of the nor-1 gene leads to accumulation of norsolorinic acid and production of reduced levels of aflatoxin Aspergillus parasiticus
1.1.1.349 metabolism the nor-I gene is functionally involved in aflatoxin biosynthesis Aspergillus parasiticus