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Literature summary extracted from

  • Zhang, F.; Snead, C.M.; Catravas, J.D.
    Hsp90 regulates O-linked beta-N-acetylglucosamine transferase: a novel mechanism of modulation of protein O-linked beta-N-acetylglucosamine modification in endothelial cells (2012), Am. J. Physiol. Cell Physiol., 302, C1786-C1796.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.255 78000
-
 2 * 110000 + 1 * 78000, SDS-PAGE Bos taurus
2.4.1.255 78000
-
 2 * 110000 + 1 * 78000, SDS-PAGE Homo sapiens
2.4.1.255 110000
-
 2 * 110000 + 1 * 78000, SDS-PAGE Bos taurus
2.4.1.255 110000
-
 2 * 110000 + 1 * 78000, SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.255 Bos taurus
-
-
-
2.4.1.255 Homo sapiens O15294
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.255 arterial endothelial cell
-
 Bos taurus
-
2.4.1.255 HLMVE cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.255 additional information heat shock protein 90 (Hsp90) is involved in the regulation of O-linked beta-N-acetylglucosamine transferase. Inhibition of Hsp90 by radicicol or 17-N-allylamino-17-demethoxygeldanamycin destabilizes the enzyme and dramatically reduces its half-life in primary cultures of endothelial cells Bos taurus ?
-
 ?
2.4.1.255 additional information heat shock protein 90 (Hsp90) is involved in the regulation of O-linked beta-N-acetylglucosamine transferase. Inhibition of Hsp90 by radicicol or 17-N-allylamino-17-demethoxygeldanamycin destabilizes the enzyme and dramatically reduces its half-life in primary cultures of endothelial cells Homo sapiens ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.1.255 heterotrimer 2 * 110000 + 1 * 78000, SDS-PAGE Bos taurus
2.4.1.255 heterotrimer 2 * 110000 + 1 * 78000, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.4.1.255 O-linked beta-N-acetylglucosamine transferase
-
 Bos taurus
2.4.1.255 O-linked beta-N-acetylglucosamine transferase
-
 Homo sapiens
2.4.1.255 OGT
-
 Bos taurus
2.4.1.255 OGT
-
 Homo sapiens