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Literature summary extracted from

  • Zhang, J.; Zhang, X.; Wu, C.; Lu, D.; Guo, G.; Mao, X.; Zhang, Y.; Wang, D.C.; Li, D.; Zou, Q.
    Expression, purification and characterization of arginase from Helicobacter pylori in its apo form (2011), PLoS ONE, 6, e26205.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.3.1 expression of apo-enzyme in a Mn2+- and Co2+-free minimal medium Helicobacter pylori

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.3.1 2-mercaptoethanol
-
 Helicobacter pylori
3.5.3.1 dithiothreitol
-
 Helicobacter pylori
3.5.3.1 Nomega-hydroxy-nor-arginine
-
 Helicobacter pylori
3.5.3.1 S-(2-boronoethyl)-L-cysteine
-
 Helicobacter pylori

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.5.3.1 Co2+ metal preference in decreasing order: Co2+, Ni2+, Mn2+. Heat-activation in presence of metal ion is essential for activation of apo-enzyme Helicobacter pylori
3.5.3.1 Mn2+ metal preference in decreasing order: Co2+, Ni2+, Mn2+. Heat-activation in presence of metal ion is essential for activation of apo-enzyme Helicobacter pylori
3.5.3.1 Ni2+ metal preference in decreasing order: Co2+, Ni2+, Mn2+. Heat-activation in presence of metal ion is essential for activation of apo-enzyme Helicobacter pylori

Organism

EC Number Organism UniProt Comment Textmining
3.5.3.1 Helicobacter pylori O25949
-
-

Subunits

EC Number Subunits Comment Organism
3.5.3.1 monomer apo-form of enzyme, gel fitlration Helicobacter pylori

Synonyms

EC Number Synonyms Comment Organism
3.5.3.1 RocF
-
 Helicobacter pylori

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.3.1 6.4
-
 apo-form of enzyme Helicobacter pylori

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.5.3.1 3
-
 no residual activity Helicobacter pylori
3.5.3.1 9
-
 50% of maximum activity Helicobacter pylori

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.5.3.1 0.01
-
 pH 7.5, 37°C Helicobacter pylori dithiothreitol
3.5.3.1 0.03
-
 pH 7.5, 37°C Helicobacter pylori 2-mercaptoethanol
3.5.3.1 0.5
-
 pH 7.5, 37°C Helicobacter pylori Nomega-hydroxy-nor-arginine
3.5.3.1 1
-
 pH 7.5, 37°C Helicobacter pylori S-(2-boronoethyl)-L-cysteine