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Literature summary extracted from

  • Meyer, C.L.; Peisker, D.; Courbot, M.; Craciun, A.R.; Cazale, A.C.; Desgain, D.; Schat, H.; Clemens, S.; Verbruggen, N.
    Isolation and characterization of Arabidopsis halleri and Thlaspi caerulescens phytochelatin synthases (2011), Planta, 234, 83-95.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.2.15 expressed in Saccharomyces cerevisiae strain BY4741 Arabidopsis halleri
2.3.2.15 expressed in Saccharomyces cerevisiae strain BY4741 Noccaea caerulescens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.2.15 Cd2+ Cd2+ activates the enzyme. Extremely efficient alternative cadmium sequestration pathways in leaves of cadmium hyperaccumulators prevent activation of phytochelatin synthase by cadmium ions Arabidopsis halleri
2.3.2.15 Cd2+ Cd2+ activates the enzyme. Extremely efficient alternative cadmium sequestration pathways in leaves of cadmium hyperaccumulators prevent activation of phytochelatin synthase by cadmium ions Noccaea caerulescens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.2.15 54000
-
x * 54000, calculated from amino acid sequence Arabidopsis halleri
2.3.2.15 54000
-
x * 54000, calculated from amino acid sequence Noccaea caerulescens

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.15 Arabidopsis halleri F1KLT6 isoform PCS2
-
2.3.2.15 Arabidopsis halleri Q56VL5 isoform PCS1
-
2.3.2.15 Noccaea caerulescens B3FMV8 isoform PCS2; formerly Thlaspi caerulescens
-
2.3.2.15 Noccaea caerulescens Q698X7 isoform PCS1; formerly Thlaspi caerulescens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.15 glutathione + [Glu(-Cys)]n-Gly
-
Arabidopsis halleri Gly + [Glu(-Cys)]n+1-Gly
-
?
2.3.2.15 glutathione + [Glu(-Cys)]n-Gly
-
Noccaea caerulescens Gly + [Glu(-Cys)]n+1-Gly
-
?

Subunits

EC Number Subunits Comment Organism
2.3.2.15 ? x * 54000, calculated from amino acid sequence Arabidopsis halleri
2.3.2.15 ? x * 54000, calculated from amino acid sequence Noccaea caerulescens

Synonyms

EC Number Synonyms Comment Organism
2.3.2.15 PCS1 isoform Noccaea caerulescens
2.3.2.15 PCS1 isoform Arabidopsis halleri
2.3.2.15 PCS2 isoform Arabidopsis halleri
2.3.2.15 PCS2 isoform Noccaea caerulescens
2.3.2.15 phytochelatin synthase
-
Arabidopsis halleri
2.3.2.15 phytochelatin synthase
-
Noccaea caerulescens

General Information

EC Number General Information Comment Organism
2.3.2.15 physiological function the enzyme is involved in cellular cadmium tolerance Arabidopsis halleri
2.3.2.15 physiological function the enzyme is involved in cellular cadmium tolerance Noccaea caerulescens